Gene Expression Literature Summary

• Symbol: Hoxa7
• Name: homeobox A7
• ID: MGI:96179

61 matching records from 61 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E6.5	E7.5	E8	E8.5	E9	E9.5	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)									1
In situ RNA (section)	1	1		1		1	1		5		10		3	1		2	1			1		1		1	3
In situ RNA (whole mount)		1	1	2	1	4	5	2	5							1
Northern blot				1			1				3		1	2		1		2		1					3
RT-PCR	1	1		3		3	4	1	2		3	1	2	3	2	1	1	1	1	2	1	1	1		7
cDNA clones		1		1		2																		1	1
RNase protection										1
Primer Extension											1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Hoxa7  homeobox A7   (Synonyms: Hox-1.1)
Results	Reference
2*	J:208763 Ahn Y, Mullan HE, Krumlauf R, Long-range regulation by shared retinoic acid response elements modulates dynamic expression of posterior Hoxb genes in CNS development. Dev Biol. 2014 Apr 1;388(1):134-44
1*	J:33159 Akasaka T, Kanno M, Balling R, Mieza MA, Taniguchi M, Koseki H, A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton. Development. 1996 MAY;122(5):1513-1522
2	J:163855 Alder O, Lavial F, Helness A, Brookes E, Pinho S, Chandrashekran A, Arnaud P, Pombo A, O'Neill L, Azuara V, Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment. Development. 2010 Aug 1;137(15):2483-92
1*	J:37508 Balling R, Mutter G, Gruss P, Kessel M, Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice. Cell. 1989 Jul 28;58(2):337-47
1	J:294517 Billingsley CN, Allen JR, Baumann DD, Deitz SL, Blazek JD, Newbauer A, Darrah A, Long BC, Young B, Clement M, Doerge RW, Roper RJ, Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome. Am J Med Genet A. 2013 Aug;161A(8):1866-74
2	J:322321 Catela C, Chen Y, Weng Y, Wen K, Kratsios P, Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife. 2022 Mar 22;11:e70766
4*	J:119560 Choi MY, Romer AI, Hu M, Lepourcelet M, Mechoor A, Yesilaltay A, Krieger M, Gray PA, Shivdasani RA, A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
6	J:8127 Colberg-Poley AM, Voss SD, Chowdhury K, Stewart CL, Wagner EF, Gruss P, Clustered homeo boxes are differentially expressed during murine development. Cell. 1985 Nov;43(1):39-45
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:138860 Dorrance AM, Liu S, Chong A, Pulley B, Nemer D, Guimond M, Yuan W, Chang D, Whitman SP, Marcucci G, Caligiuri MA, The Mll partial tandem duplication: differential, tissue-specific activity in the presence or absence of the wild-type allele. Blood. 2008 Sep 15;112(6):2508-11
2	J:115001 Dorrance AM, Liu S, Yuan W, Becknell B, Arnoczky KJ, Guimond M, Strout MP, Feng L, Nakamura T, Yu L, Rush LJ, Weinstein M, Leone G, Wu L, Ferketich A, Whitman SP, Marcucci G, Caligiuri MA, Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. J Clin Invest. 2006 Oct;116(10):2707-16
6*	J:31004 Dressler GR, Gruss P, Anterior boundaries of Hox gene expression in mesoderm-derived structures correlate with the linear gene order along the chromosome. Differentiation. 1989 Sep;41(3):193-201
1*	J:157035 Fisher CL, Lee I, Bloyer S, Bozza S, Chevalier J, Dahl A, Bodner C, Helgason CD, Hess JL, Humphries RK, Brock HW, Additional sex combs-like 1 belongs to the enhancer of trithorax and polycomb group and genetically interacts with Cbx2 in mice. Dev Biol. 2010 Jan 1;337(1):9-15
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1*	J:55152 Gaunt SJ, Dean W, Sang H, Burton RD, Evidence that Hoxa expression domains are evolutionarily transposed in spinal ganglia, and are established by forward spreading in paraxial mesoderm. Mech Dev. 1999 Apr;82(1-2):109-18
1	J:12603 Goto J, Miyabayashi T, Wakamatsu Y, Takahashi N, Muramatsu M, Organization and expression of mouse Hox3 cluster genes. Mol Gen Genet. 1993 May;239(1-2):41-8
1	J:30824 Grass S, Arnold HH, Braun T, Alterations in somite patterning of Myf-5-deficient mice: a possible role for FGF-4 and FGF-6. Development. 1996 Jan;122(1):141-50
2*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
5*	J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2	J:308865 Higashijima Y, Nagai N, Yamamoto M, Kitazawa T, Kawamura YK, Taguchi A, Nakada N, Nangaku M, Furukawa T, Aburatani H, Kurihara H, Wada Y, Kanki Y, Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster. Commun Biol. 2020 Nov 30;3(1):725
2	J:166088 Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S, Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H, Dasen JS, Global control of motor neuron topography mediated by the repressive actions of a single hox gene. Neuron. 2010 Sep 9;67(5):781-96
1	J:162938 Kang X, Qi Y, Zuo Y, Wang Q, Zou Y, Schwartz RJ, Cheng J, Yeh ET, SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell. 2010 Apr 23;38(2):191-201
1*	J:31643 Kessel M, Respecification of vertebral identities by retinoic acid. Development. 1992 Jun;115(2):487-501
1*	J:2748 Kessel M, Gruss P, Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell. 1991 Oct 4;67(1):89-104
1	J:173414 Kondrashov N, Pusic A, Stumpf CR, Shimizu K, Hsieh AC, Xue S, Ishijima J, Shiroishi T, Barna M, Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning. Cell. 2011 Apr 29;145(3):383-97
1	J:114902 Kong CT, Sham MH, So CW, Cheah KS, Chen SJ, Chan LC, The Mll-Een knockin fusion gene enhances proliferation of myeloid progenitors derived from mouse embryonic stem cells and causes myeloid leukaemia in chimeric mice. Leukemia. 2006 Oct;20(10):1829-39
1	J:195163 Lacombe J, Hanley O, Jung H, Philippidou P, Surmeli G, Grinstein J, Dasen JS, Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. PLoS Genet. 2013 Jan;9(1):e1003184
2*	J:226028 Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA, Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
1*	J:58846 Li ZL, Shiota K, Stage-specific homeotic vertebral transformations in mouse fetuses induced by maternal hyperthermia during somitogenesis. Dev Dyn. 1999 Dec;216(4-5):336-48
1*	J:291732 Lin Y, Yu J, Wu J, Wang S, Zhang T, Abnormal level of CUL4B-mediated histone H2A ubiquitination causes disruptive HOX gene expression. Epigenetics Chromatin. 2019 Apr 16;12(1):22
1	J:145579 Madan V, Madan B, Brykczynska U, Zilbermann F, Hogeveen K, Dohner K, Dohner H, Weber O, Blum C, Rodewald HR, Sassone-Corsi P, Peters AH, Fehling HJ, Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5. Blood. 2009 Feb 12;113(7):1444-54
2	J:42706 McGrath KE, Palis J, Expression of homeobox genes, including an insulin promoting factor, in the murine yolk sac at the time of hematopoietic initiation. Mol Reprod Dev. 1997 Oct;48(2):145-53
7*	J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66
2	J:247259 Naruse C, Shibata S, Tamura M, Kawaguchi T, Abe K, Sugihara K, Kato T, Nishiuchi T, Wakana S, Ikawa M, Asano M, New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice. FASEB J. 2017 Jun;31(6):2252-2266
3*	J:23968 Parikh H, Shah S, Hilt D, Peterkofsky A, Organization, sequence and regulation of expression of the murine Hoxa-7 gene. Gene. 1995 Mar 10;154(2):237-42
4*	J:89197 Patterson LT, Potter SS, Atlas of Hox gene expression in the developing kidney. Dev Dyn. 2004 Apr;229(4):771-9
1*	J:187969 Pazin DE, Gamer LW, Cox KA, Rosen V, Molecular profiling of synovial joints: Use of microarray analysis to identify factors that direct the development of the knee and elbow. Dev Dyn. 2012 Nov;241(11):1816-26
1	J:18886 Pellerin I, Schnabel C, Catron KM, Abate C, Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster. Mol Cell Biol. 1994 Jul;14(7):4532-45
1*	J:76367 Rathjen J, Haines BP, Hudson KM, Nesci A, Dunn S, Rathjen PD, Directed differentiation of pluripotent cells to neural lineages: homogeneous formation and differentiation of a neurectoderm population. Development. 2002 Jun;129(11):2649-61
1	J:290220 Sato T, Kataoka K, Ito Y, Yokoyama S, Inui M, Mori M, Takahashi S, Akita K, Takada S, Ueno-Kudoh H, Asahara H, Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates. Elife. 2020 May 29;9:e53608
1	J:106551 Satoh W, Gotoh T, Tsunematsu Y, Aizawa S, Shimono A, Sfrp1 and Sfrp2 regulate anteroposterior axis elongation and somite segmentation during mouse embryogenesis. Development. 2006 Mar;133(6):989-99
1	J:33051 Schnabel CA, Abate-Shen C, Repression by HoxA7 is mediated by the homeodomain and the modulatory action of its N-terminal-arm residues. Mol Cell Biol. 1996 Jun;16(6):2678-88
3	J:181230 Scotti M, Kmita M, Recruitment of 5' Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammals. Development. 2012 Feb;139(4):731-9
4*	J:218555 Sheikh BN, Downer NL, Kueh AJ, Thomas T, Voss AK, Excessive versus physiologically relevant levels of retinoic acid in embryonic stem cell differentiation. Stem Cells. 2014 Jun;32(6):1451-8
4*	J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1*	J:29755 Subramanian V, Meyer BI, Gruss P, Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell. 1995 Nov 17;83(4):641-53
1	J:109102 Terranova R, Agherbi H, Boned A, Meresse S, Djabali M, Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6629-34
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:127131 Ueda T, Watanabe-Fukunaga R, Ogawa H, Fukuyama H, Higashi Y, Nagata S, Fukunaga R, Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis. Genes Cells. 2007 May;12(5):581-92
2	J:35539 van der Lugt NM, Alkema M, Berns A, Deschamps J, The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression. Mech Dev. 1996 Aug;58(1-2):153-64
1	J:78736 Wang J, Mager J, Schnedier E, Magnuson T, The mouse PcG gene eed is required for Hox gene repression and extraembryonic development. Mamm Genome. 2002 Sep;13(9):493-503
2	J:4189 Watrin F, Wolgemuth DJ, Conservation and divergence of patterns of expression and lineage-specific transcripts in orthologues and paralogues of the mouse Hox-1.4 gene. Dev Biol. 1993 Mar;156(1):136-45
1	J:226712 Wong SF, Agarwal V, Mansfield JH, Denans N, Schwartz MG, Prosser HM, Pourquie O, Bartel DP, Tabin CJ, McGlinn E, Independent regulation of vertebral number and vertebral identity by microRNA-196 paralogs. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4884-93
1	J:248225 Xi S, Zhu H, Xu H, Schmidtmann A, Geiman TM, Muegge K, Lsh controls Hox gene silencing during development. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14366-71
1	J:48502 Yagi H, Deguchi K, Aono A, Tani Y, Kishimoto T, Komori T, Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice. Blood. 1998 Jul 1;92(1):108-17
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
2	J:314242 Yoshioka K, Nagahisa H, Miura F, Araki H, Kamei Y, Kitajima Y, Seko D, Nogami J, Tsuchiya Y, Okazaki N, Yonekura A, Ohba S, Sumita Y, Chiba K, Ito K, Asahina I, Ogawa Y, Ito T, Ohkawa Y, Ono Y, Hoxa10 mediates positional memory to govern stem cell function in adult skeletal muscle. Sci Adv. 2021 Jun;7(24)
3*	J:49977 Yu BD, Hanson RD, Hess JL, Horning SE, Korsmeyer SJ, MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10632-6
2	J:29958 Yu BD, Hess JL, Horning SE, Brown GA, Korsmeyer SJ, Altered Hox expression and segmental identity in Mll-mutant mice. Nature. 1995 Nov 30;378(6556):505-8
1	J:225113 Zhang Y, Liu Z, Medrzycki M, Cao K, Fan Y, Reduction of Hox gene expression by histone H1 depletion. PLoS One. 2012;7(6):e38829