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Fgf5 Gene Detail
Summary
  • Symbol
    Fgf5
  • Name
    fibroblast growth factor 5
  • Synonyms
    Fgf-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:95519
    NCBI Gene: 14176
  • Gene Overview
    MyGene.info: FGF5
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:98254184-98277030 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      22847 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 47.77 cM, cytoband E1-F
  • Mapping Data
    27 experiments
Homology
more
  • Human Ortholog
    FGF5, fibroblast growth factor 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FGF5, fibroblast growth factor 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HBGF-5, Smag-82, TCMGLY
  • Links
    NCBI Gene ID: 2250
    neXtProt AC: NX_P12034
    UniProt: P12034

  • Chr Location
    4q21.21; chr4:80266588-80291017 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 6 alleles in 6 genetic backgrounds
    1 phenotype from multigenic genotypes
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mutations in this gene result in significantly longer pelage hair.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
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    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000053547 VEGA Gene Model | MGI Sequence Detail 22847 C57BL/6J ±  kb
    transcript OTTMUST00000133510 VEGA | MGI Sequence Detail 2501 Not Applicable  
    polypeptide OTTMUSP00000070947 VEGA | MGI Sequence Detail 264 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      328 from dbSNP Build 142
    • RFLP
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 41
      Genomic 5
      cDNA 22
      Primer pair 9
      Other 5

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-10212, MGD-MRK-9764, MGD-MRK-9770
    References
    more
    • Summaries
      All 134
      Developmental Gene Expression 52
      Gene Ontology 6
      Phenotypes 26
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:262209 Whittaker DE, et al., Distinct cerebellar foliation anomalies in a CHD7 haploinsufficient mouse model of CHARGE syndrome. Am J Med Genet C Semin Med Genet. 2017 Dec;175(4)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    07/31/2018
    MGI 6.12
    The Jackson Laboratory