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Fcer1g
Gene Detail
Symbol

Name
ID
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
MGI:95496
Synonyms
Fce1g, FcepsilonRI, FcR[g], FcRgamma, FcR-gamma, Ly-50
Feature Type
protein coding gene
Genetic Map
Chromosome 1
79.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(15)
Sequence Map
Chr1:171229572-171234365 bp, - strand
From VEGA annotation of GRCm38

  4794 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3029  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: FCER1G
Protein SuperFamily: high affinity immunoglobulin epsilon receptor gamma-subunit
Gene Tree: Fcer1g

Human
homologs
FCER1G, Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 2207
neXtProt AC: NX_P30273

Human Synonyms: FCRG

Human Chr (Location): 1q23; chr1:161215297-161219248 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations exhibit impairments in macrophage phagocytosis, NK cell-mediated antibody-coated cytotoxicity, mast cell degranulation, IgE-mediated systemic anaphylaxis, and neutrophil recruitment and migration.
 
Mutations Annotated to Human Diseases (1)   
Interactions
Fcer1g interacts with 44 markers (Mir137, Mir185, Mir188, ...)
Expression
Literature Summary: (1 records)
Data Summary: Results (38)    Tissues (24)    Images (11)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 38
cDNA source data(28)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: ZFIN fcer1g    NEW 
Molecular
reagents
All nucleic(33) Genomic(2) cDNA(30) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000021504 (Evidence)
Ensembl Gene Model ENSMUSG00000058715 (Evidence)
Entrez Gene 14127 (Evidence)
UniGene 22673
DFCI TC1580648, TC1587621
DoTS DT.531420
NIA Mouse Gene Index U161999
Consensus CDS Project CCDS15483.1
International Mouse Phenotyping Consortium Status Fcer1g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021504 VEGA Gene Model | MGI Sequence Detail 4794 C57BL/6J ±  kb
transcript OTTMUST00000127196 VEGA | MGI Sequence Detail 683 Not Applicable 
polypeptide OTTMUSP00000068685 VEGA | MGI Sequence Detail 92 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(2)
Polymorphisms
RFLP(2) : SNPs within 2kb(109 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003110 Phosphorylated immunoreceptor signalling ITAM
InterPro IPR021663 T-cell surface glycoprotein CD3 zeta/eta subunit/High affinity IgE receptor gamma subunit
Protein Ontology PR:000007432 high affinity immunoglobulin epsilon receptor subunit gamma
References
(Earliest) J:8413 Hibbs ML, et al., The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones. Proc Natl Acad Sci U S A. 1986 Sep;83(18):6980-4
(Latest) J:221858 Negishi-Koga T, et al., Immune complexes regulate bone metabolism through FcRgamma signalling. Nat Commun. 2015;6:6637
All references(377)
Other
accession IDs
MGD-MRK-11993, MGD-MRK-9726, MGD-MRK-9730, MGI:2138290

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory