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Fcer1g
Gene Detail
 Symbol
Name
ID
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
MGI:95496
Synonyms Fce1g, FcepsilonRI, FcR[g], FcRgamma, FcR-gamma, Ly-50
Feature Type protein coding gene
Genetic Map
Chromosome 1
79.23 cM
Detailed Genetic Map ± 1 cM


Mapping data(15)
Sequence Map
Chr1:171229572-171234365 bp, - strand
From VEGA annotation of GRCm38

  4794 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3029  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Protein SuperFamily: high affinity immunoglobulin epsilon receptor gamma-subunit
Gene Tree: Fcer1g

Human
homologs
Human Homolog FCER1G, Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
NCBI Gene ID 2207
neXtProt AC  NX_P30273
Human Synonyms  FCRG
Human Chr (Location)  1q23; chr1:161215297-161219248 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for targeted null mutations exhibit impairments in macrophage phagocytosis, NK cell-mediated antibody-coated cytotoxicity, mast cell degranulation, IgE-mediated systemic anaphylaxis, and neutrophil recruitment and migration.
 
Alleles Annotated to Human Diseases(1)   
Interactions
Fcer1g interacts with 44 markers (Mir137, Mir185, Mir188, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (62 annotations)
Process antigen processing and presentation of exogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via MHC class II, ...
Component cell surface, external side of plasma membrane, ...
Function IgE binding, IgE receptor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (38)    Tissues (24)    Images (11)
Theiler Stages: 23, 28
Assay TypeResults
RNA in situ 38
cDNA source data(28)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) Genomic(2) cDNA(30) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021504 (Evidence)
Ensembl Gene ModelENSMUSG00000058715 (Evidence)
Entrez Gene14127 (Evidence)
UniGene22673
DFCITC1580648, TC1587621
DoTSDT.531420
NIA Mouse Gene IndexU161999
Consensus CDS ProjectCCDS15483.1
International Mouse Knockout Project StatusFcer1g
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021504 VEGA Gene Model | MGI Sequence Detail 4794 C57BL/6J ±  kb
transcript OTTMUST00000050975 VEGA | MGI Sequence Detail 674 Not Applicable 
polypeptide OTTMUSP00000023927 VEGA | MGI Sequence Detail 86 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(4) UniProt(1)
Polymorphisms RFLP(2) : SNPs within 2kb(109 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003110 Phosphorylated immunoreceptor signaling ITAM
InterPro IPR021663 T-cell surface glycoprotein CD3 zeta/eta subunit/High affinity IgE receptor gamma subunit
Protein Ontology PR:000007432 high affinity immunoglobulin epsilon receptor subunit gamma
References (Earliest) J:8413 Hibbs ML, et al., The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones. Proc Natl Acad Sci U S A. 1986 Sep;83(18):6980-4
(Latest) J:209615 Bezbradica JS, et al., A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat Immunol. 2014 Apr;15(4):333-42
All references(366)
Other
accession IDs
MGD-MRK-11993, MGD-MRK-9726, MGD-MRK-9730, MGI:2138290

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory