Fcer1g Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
MGI:95496

51 phenotypes from 3 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fcer1g^{tm1b(KOMP)Wtsi}/Fcer1g^{tm1b(KOMP)Wtsi} C57BL/6N-Fcer1g^{tm1b(KOMP)Wtsi}/Ucd	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Fcer1g^tm1Rav/Fcer1g^tm1Rav B6.129P2-Fcer1g^tm1Rav	decreased interleukin-1 beta secretion	J:160680
	decreased interleukin-6 secretion	J:160680
	decreased interleukin-10 secretion	J:160680
	decreased interleukin-12b secretion	J:160680
	decreased interleukin-23 secretion	J:160680
	decreased tumor necrosis factor secretion	J:160680
Fcer1g^tm1Rav/Fcer1g^tm1Rav involves: 129P2/OlaHsd	abnormal hemoglobin	J:168556
	decreased platelet aggregation	J:165893
	hematoma	J:168556
	increased susceptibility to parasitic infection	J:163761
	normal skeleton phenotype	J:197378
Fcer1g^tm1Rav/Fcer1g^tm1Rav involves: 129P2/OlaHsd * C57BL/6	abnormal dendritic cell antigen presentation	J:83995
	abnormal immune cell physiology	J:39248
	abnormal immunoglobulin level	J:78659
	abnormal mast cell physiology	J:39248
	abnormal NK cell physiology	J:39248
	abnormal platelet activation	J:118488
	decreased myocardial infarct size	J:112819
	decreased platelet aggregation	J:112819
	decreased platelet calcium level	J:118488
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:126520
	decreased susceptibility to type I hypersensitivity reaction	J:39248, J:78659
	normal immune system phenotype	J:28282
	impaired macrophage phagocytosis	J:39248
	increased IgE level	J:78659
	normal skeleton phenotype	J:89583
Fcer1g^tm1Tks/Fcer1g^tm1Tks C57BL/6-Fcer1g^tm1Tks	decreased susceptibility to autoimmune hemolytic anemia	J:145432
Fcer1g^tm1Tks/Fcer1g^tm1Tks involves: C57BL/6	abnormal antigen presentation	J:112160
	abnormal CD4-positive, alpha-beta T cell physiology	J:112160
	abnormal chemokine secretion	J:141143
	abnormal cytokine level	J:258645
	abnormal macrophage physiology	J:141143
	abnormal NK cell physiology	J:111365
	abnormal NK T cell physiology	J:111365
	decreased IgG1 level	J:112160
	decreased IgG2a level	J:112160
	decreased IgG2b level	J:112160
	decreased IgG3 level	J:112160
	decreased IgG level	J:112160
	decreased inflammatory response	J:50023
	decreased interferon-gamma secretion	J:111365, J:112160
	decreased interleukin-2 secretion	J:112160
	decreased susceptibility to induced morbidity/mortality	J:50023
	decreased susceptibility to type IV hypersensitivity reaction	J:112160
	decreased T cell proliferation	J:112160
	impaired macrophage phagocytosis	J:50023
	impaired natural killer cell mediated cytotoxicity	J:111365
Fcer1g^tm1Tks/Fcer1g^tm1Tks involves: C57BL/6J	abnormal chemokine secretion	J:203159
	abnormal interferon-gamma secretion	J:203159
	abnormal interleukin-17 secretion	J:203159
	decreased dendritic cell number	J:203159
	decreased physiological sensitivity to xenobiotic	J:203159
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:203159
	decreased tumor necrosis factor secretion	J:203159

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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