Homozygotes for spontaneous, chemically-induced, and targeted null mutations show bilateral syndactyly with fusion of both soft and hard tissues. Deafness found in an X-ray induced allelic mutant is apparently due to the joint disruption of a linked gene.
|InterPro||IPR026823||Complement Clr-like EGF domain|
|InterPro||IPR018097||EGF-like calcium-binding, conserved site|
|InterPro||IPR013032||EGF-like, conserved site|
|InterPro||IPR000152||EGF-type aspartate/asparagine hydroxylation site|
|InterPro||IPR000742||Epidermal growth factor-like domain|
|InterPro||IPR009030||Insulin-like growth factor binding protein, N-terminal|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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