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Emx1
Gene Detail
 Symbol
Name
ID
Emx1
empty spiracles homeobox 1
MGI:95387
Feature Type protein coding gene
Genetic Map
Chromosome 6
37.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:85187438-85204462 bp, + strand
From VEGA annotation of GRCm38

  17025 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55799  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Emx1

Human
homologs
Human Homolog EMX1, empty spiracles homeobox 1
NCBI Gene ID 2016
neXtProt AC  NX_Q04741
Human Chr (Location)  2p13.2; chr2:72917475-72934891 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Targeted(10)
Incidental mutations (data from Mutagenetix , APF )
 
Mice with this mutation are viable and fertile.
 
Alleles Annotated to Human Diseases(1)   
Interactions
Emx1 interacts with 50 markers (Mir7-1, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process brain development, brain morphogenesis, ...
Component nucleus
Function DNA binding, sequence-specific DNA binding
External Resources: FuncBase
Expression
Literature Summary: (80 records)
Data Summary: Results (169)    Tissues (77)    Images (48)
Theiler Stages: 15, 16, 17, 19, 20, 21, 22, 23, 24, 25, 27, 28
Assay TypeResults
Immunohistochemistry 3
RNA in situ 144
In situ reporter (knock in) 11
Northern blot 2
RT-PCR 9
cDNA source data(14)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(16) Primer pair(4) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000037267 (Evidence)
Ensembl Gene ModelENSMUSG00000033726 (Evidence)
Entrez Gene13796 (Evidence)
UniGene391473
DFCITC1588999
DoTSDT.101264688, DT.110501286
NIA Mouse Gene IndexU007099
Consensus CDS ProjectCCDS20290.1
International Mouse Knockout Project StatusEmx1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037267 VEGA Gene Model | MGI Sequence Detail 17025 C57BL/6J ±  kb
transcript OTTMUST00000096120 VEGA | MGI Sequence Detail 1561 Not Applicable 
polypeptide OTTMUSP00000053665 VEGA | MGI Sequence Detail 257 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(52 from dbSNP Build 137)    SNPs within 2kb including multiple locations(54)
Protein-related
information
ResourceIDDescription
InterPro IPR017970 Homeobox, conserved site
InterPro IPR001356 Homeodomain
InterPro IPR009057 Homeodomain-like
InterPro IPR020479 Homeodomain, metazoa
Protein Ontology PR:000007068 homeobox protein EMX1
References (Earliest) J:1461 Simeone A, et al., Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 1992 Jul;11(7):2541-50
(Latest) J:212315 Gee JM, et al., Imaging Activity in Neurons and Glia with a Polr2a-Based and Cre-Dependent GCaMP5G-IRES-tdTomato Reporter Mouse. Neuron. 2014 Aug 20;
All references(314)
Other
accession IDs
MGD-MRK-9495

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory