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Galnt3
Gene Detail
Symbol

Name
ID
Galnt3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
MGI:894695
Synonyms
ppGaNTase-T3
Feature Type
protein coding gene
Genetic Map
Chromosome 2
38.99 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:66082766-66124994 bp, - strand
From VEGA annotation of GRCm38

  42229 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55827  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Galnt3

Human
homologs
Human Homolog GALNT3, polypeptide N-acetylgalactosaminyltransferase 3
NCBI Gene ID 2591
neXtProt AC  NX_Q14435
Human Synonyms  GalNAc-T3, HFTC, HHS
Human Chr (Location)  2q24-q31; chr2:165747803-165794293 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Chemically induced (ENU)(1) Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased circulating alkaline phosphatase, hypercalcemia, hyperphosphatemia, decreased circulating parathyroid hormone, and male specific postnatal growth retardation, infertility, and increase in bone density.
 
Human Diseases Modeled Using Mouse Galnt3 (1)    Alleles Annotated to Human Diseases(2)    Phenotype Images(2)
Interactions
Galnt3 interacts with 233 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (2 records)
Data Summary: Results (103)    Tissues (102)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 103
cDNA source data(74)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(75) cDNA(74) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000013003 (Evidence)
Ensembl Gene ModelENSMUSG00000026994 (Evidence)
Entrez Gene14425 (Evidence)
UniGene439760
DFCITC1685051, TC1613957, TC1579663, TC1739721
DoTSDT.524355, DT.91330028, DT.94251897
NIA Mouse Gene IndexU022693
EC2.4.1.41
Consensus CDS ProjectCCDS16075.1
International Mouse Knockout Project StatusGalnt3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013003 VEGA Gene Model | MGI Sequence Detail 42229 C57BL/6J ±  kb
transcript OTTMUST00000031330 VEGA | MGI Sequence Detail 3885 Not Applicable 
polypeptide OTTMUSP00000014011 VEGA | MGI Sequence Detail 633 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(3) UniProt(1)
Polymorphisms
SNPs within 2kb(388 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001173 Glycosyl transferase, family 2
InterPro IPR000772 Ricin B lectin domain
Protein Ontology PR:000007825 polypeptide N-acetylgalactosaminyltransferase 3
References
(Earliest) J:36626 Zara J, et al., Cloning and expression of mouse UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T3. Biochem Biophys Res Commun. 1996 Nov 1;228(1):38-44
(Latest) J:196643 Ichikawa S, et al., A Phex mutation in a murine model of X-linked hypophosphatemia alters phosphate responsiveness of bone cells. J Bone Miner Res. 2012 Feb;27(2):453-60
All references(39)
Disease annotation references (2)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory