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Sstr5
Gene Detail
 Symbol
Name
ID
Sstr5
somatostatin receptor 5
MGI:894282
Synonyms Smstr5, sst5
Feature Type protein coding gene
Genetic Map
Chromosome 17
12.62 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:25489875-25497288 bp, - strand
From NCBI annotation of GRCm38

  7414 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20287  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: somatostatin receptor
Gene Tree: Sstr5

Human
homologs
Human Homolog SSTR5, somatostatin receptor 5
NCBI Gene ID 6755
neXtProt AC  NX_P35346
Human Synonyms  SS-5-R
Human Chr (Location)  16p13.3; chr16:1072756-1081454 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SSTR5
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Radiation induced(2) Targeted(5)
Genomic Mutations involving Sstr5 (2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygotes for one null allele display decreased numbers of insulin positive cells in the pancreas. Homozygotes for a second null allele have normal pancreatic islet morphology but increased insulin secretion, decreased blood insulin and glucose levels, and improved glucose tolerance.
 
Interactions
Sstr5 interacts with 98 markers (Mir7-2, Mir15b, Mir23a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, glucose homeostasis, ...
Component cytoplasm, integral component of membrane, ...
Function G-protein coupled receptor activity, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) Genomic(4) cDNA(5) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000050824 (Evidence)
Entrez Gene20609 (Evidence)
DFCITC1588294
DoTSDT.55251618, DT.94135256
NIA Mouse Gene IndexU049078
Consensus CDS ProjectCCDS28520.1
International Mouse Knockout Project StatusSstr5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 20609 NCBI Gene Model | MGI Sequence Detail 7414 C57BL/6J ±  kb
transcript NM_011425 RefSeq | MGI Sequence Detail 2733 C57BL/6 
polypeptide O08858 UniProt | EBI | MGI Sequence Detail 362 Not Applicable 

For the selected sequences
All sequences(31) RefSeq(6) UniProt(3)
Polymorphisms RFLP(1) : SNPs within 2kb(130 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001184 Somatostatin receptor 5
InterPro IPR000586 Somatostatin receptor family
Protein Ontology PR:000001672 somatostatin receptor type 5
Graphical View of Protein Domain Structure
References (Earliest) J:41656 Brinkmeier ML, et al., Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs. Genomics. 1997 Jul 1;43(1):9-14
(Latest) J:185665 Guo Z, et al., Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20
All references(47)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory