Sstr5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sstr5
somatostatin receptor 5
MGI:894282

17 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Sstr5^em1(IMPC)Mbp/\Sstr5^em1(IMPC)Mbp C57BL/6N-Sstr5^em1(IMPC)Mbp/MbpMmucd	decreased startle reflex	J:211773
\Sstr5^tm1Fcb/\Sstr5^tm1Fcb involves: 129	abnormal pancreatic alpha cell morphology	J:179577
	normal homeostasis/metabolism phenotype	J:179577
	increased insulin secretion	J:179577
\Sstr5^tm1Fcb/\Sstr5^tm1Fcb involves: 129 * C57BL/6J	decreased pancreatic beta cell number	J:91762
\Sstr5^tm1Fcb/\Sstr5^tm2Fcb \Tg(Ins2-cre)1Heed/0 involves: 129S7/SvEvBrd * C57BL/6 * CBA	abnormal insulin clearance	J:99786
	decreased circulating glucose level	J:99786
	decreased insulin secretion	J:99786
	decreased pancreatic delta cell number	J:99786
	impaired glucose tolerance	J:99786
	increased circulating insulin level	J:99786
	increased insulin secretion	J:99786
\Sstr5^tm1Hawi/\Sstr5^tm1Hawi involves: 129S7/SvEvBrd * C57BL/6J	decreased body weight	J:101259
	decreased circulating glucose level	J:101259
	decreased circulating insulin level	J:101259
	improved glucose tolerance	J:101259
	increased circulating glucagon level	J:101259
	increased circulating leptin level	J:101259
	increased insulin secretion	J:101259
	increased insulin sensitivity	J:101259

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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