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Cyp3a11 Gene Detail
Summary
  • Symbol
    Cyp3a11
  • Name
    cytochrome P450, family 3, subfamily a, polypeptide 11
  • Synonyms
    Cyp3a, IIIAm1, Pcn
  • Feature Type
    protein coding gene
  • IDs
    MGI:88609
    NCBI Gene: 13112
  • Gene Overview
    MyGene.info: CYP3A5
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:145854607-145879854 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 85.17 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    147 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88609
protein coding gene Chr5:145854426-145879964 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030368
protein coding gene Chr5:151307465-151351559 (-)
A/J MGP_AJ_G0030339
protein coding gene Chr5:144872570-144910465 (-)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0030064
protein coding gene Chr5:149738794-149811248 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030799
protein coding gene Chr5:156908140-156935228 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0030035
protein coding gene Chr5:163232878-163318534 (-)
DBA/2J MGP_DBA2J_G0030188
protein coding gene Chr5:144580441-144605385 (-)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0030170
protein coding gene Chr5:165161039-165239719 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0029544
protein coding gene Chr5:150072907-150097199 (-)



Homology
more
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
    Orthology source: HomoloGene
  • Synonyms
    CP35, CYPIIIA5, P450PCN3, PCN3
  • Links
    NCBI Gene ID: 1577
    neXtProt AC: NX_P20815
    UniProt: P20815

  • Chr Location
    7q22.1; chr7:99648189-99680026 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human CYP3A5 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13112 NCBI Gene Model | MGI Sequence Detail 25248 C57BL/6J ±  kb
transcript NM_007818 RefSeq | MGI Sequence Detail 2053 C57BL/6  
polypeptide Q64459 UniProt | EBI | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 103
    Genomic 4
    cDNA 97
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13177, MGD-MRK-2330, MGD-MRK-2331, MGI:2140820
References
more
  • Summaries
    All 59
    Developmental Gene Expression 10
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:7687 Simmons DL, et al., Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes. J Biol Chem. 1985 Jan 10;260(1):515-21
  • Latest
    J:277988 Zurkinden L, et al., Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice. Biosci Rep. 2018 Feb 28;38(1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory