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Cyp3a11
Gene Detail
 Symbol
Name
ID
Cyp3a11
cytochrome P450, family 3, subfamily a, polypeptide 11
MGI:88609
Synonyms Cyp3a, IIIAm1, Pcn
Feature Type protein coding gene
Genetic Map
Chromosome 5
85.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr5:145854426-145879964 bp, - strand
From VEGA annotation of GRCm38

  25539 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:133568  Vertebrate Homology Class
1 human; 5 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: cytochrome P450 CYP3A5
Gene Tree: Cyp3a11

Human
homologs
Human Homolog CYP3A5, cytochrome P450, family 3, subfamily A, polypeptide 5
NCBI Gene ID 1577
neXtProt AC  NX_P20815
Human Synonyms  CP35, CYPIIIA5, P450PCN3, PCN3
Human Chr (Location)  7q21.1; chr7:99648190-99679998 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYP3A5
Alleles
and
phenotypes
All alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process demethylation, oxidation-reduction process
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function aromatase activity, demethylase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (236)    Tissues (151)    Images (38)
Theiler Stages: 10, 18, 22, 23, 25, 26, 28
Assay TypeResults
RNA in situ 203
Northern blot 2
RT-PCR 12
Nuclease S1 19
cDNA source data(95)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(101) Genomic(4) cDNA(96) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000026077 (Evidence)
Ensembl Gene ModelENSMUSG00000056035 (Evidence)
Entrez Gene13112 (Evidence)
UniGene332844
DoTSDT.87079120
NIA Mouse Gene IndexU156504
EC1.14.14.1
Consensus CDS ProjectCCDS19865.1
International Mouse Knockout Project StatusCyp3a11
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026077 VEGA Gene Model | MGI Sequence Detail 25539 C57BL/6J ±  kb
transcript OTTMUST00000064371 VEGA | MGI Sequence Detail 2344 Not Applicable 
polypeptide OTTMUSP00000031951 VEGA | MGI Sequence Detail 504 Not Applicable 

For the selected sequences
All sequences(20) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(161 from dbSNP Build 137)    SNPs within 2kb including multiple locations(173)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR008072 Cytochrome P450, E-class, CYP3A
InterPro IPR002402 Cytochrome P450, E-class, group II
Protein Ontology PR:000006241 cytochrome P450 3A11
References (Earliest) J:7687 Simmons DL, et al., Chromosomal assignments of genes coding for components of the mixed-function oxidase system in mice. Genetic localization of the cytochrome P-450PCN and P-450PB gene families and the nadph-cytochrome P-450 oxidoreductase and epoxide hydratase genes. J Biol Chem. 1985 Jan 10;260(1):515-21
(Latest) J:208341 Seth A, et al., Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment. Development. 2014 Feb;141(3):538-47
All references(44)
Other
accession IDs
MGD-MRK-13177, MGD-MRK-2330, MGD-MRK-2331, MGI:2140820

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory