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Cyp2d9
Gene Detail
Symbol

Name
ID
Member of
Cyp2d9
cytochrome P450, family 2, subfamily d, polypeptide 9
MGI:88606
Cyp2d cluster
Synonyms
Cyp2d, P450-2D, testosterone 16alpha-hydroxylase
Feature Type
protein coding gene
Genetic Map
Chromosome 15
38.60 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr15:82452377-82456827 bp, + strand
From NCBI annotation of GRCm38

  4451 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:86099  Vertebrate Homology Class
5 mouse

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2d9

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Radiation induced(1)
Genomic Mutations involving Cyp2d9 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Cyp2d9 interacts with 33 markers (Mir127, Mir191, Mir205, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function aromatase activity, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (128)    Tissues (107)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 116
RT-PCR 12
cDNA source data(307)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(311) Genomic(3) cDNA(307) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000068086 (Evidence)
Entrez Gene13105 (Evidence)
UniGene226708
DoTSDT.101132950, DT.102537080, DT.87052392, DT.94219384
NIA Mouse Gene IndexU138945
EC1.14.14.1
Consensus CDS ProjectCCDS27691.1
International Mouse Knockout Project StatusCyp2d9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 13105 NCBI Gene Model | MGI Sequence Detail 4451 C57BL/6J ±  kb
transcript NM_010006 RefSeq | MGI Sequence Detail 1651 C57BL/6 
polypeptide P11714 UniProt | EBI | MGI Sequence Detail 504 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(2) UniProt(3)
Polymorphisms
RFLP(2) : SNPs within 2kb(115 from dbSNP Build 137)    SNPs within 2kb including multiple locations(159)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
Protein Ontology PR:000006237 cytochrome P450 2D9
Graphical View of Protein Domain Structure
References
(Earliest) J:7796 Harada N, et al., Sex-dependent expression of mouse testosterone 16 alpha-hydroxylase (cytochrome P-450(16) alpha): cDNA cloning and pretranslational regulation. Proc Natl Acad Sci U S A. 1985 Apr;82(7):2024-8
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(39)
Other
accession IDs
MGD-MRK-13111, MGD-MRK-2325

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory