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Cyp2d12 Gene Detail
Summary
  • Symbol
    Cyp2d12
  • Name
    cytochrome P450, family 2, subfamily d, polypeptide 12
  • Synonyms
    9030605E09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:88604
    NCBI Gene: 380997
  • Member of
    Cyp2d cluster
Location & Maps
more
  • Sequence Map
    Chr15:82555108-82559413 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4306 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 38.64 cM
  • Mapping Data
    1 experiment
Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    18 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Cyp2d12
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000096852 Ensembl Gene Model | MGI Sequence Detail 4306 C57BL/6J ±  kb
transcript ENSMUST00000068861 Ensembl | MGI Sequence Detail 1614 Not Applicable  
polypeptide ENSMUSP00000071064 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    37 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-2323, MGI:3584268
References
more
  • Summaries
    All 13
    Diseases 1
    Gene Ontology 1
    Phenotypes 18
  • Earliest
    J:4152 Nelson DR, et al., The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol. 1993 Jan-Feb;12(1):1-51
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory