Cyp2d12
Gene Detail

Symbol Name ID

Cyp2d12 cytochrome P450, family 2, subfamily d, polypeptide 12 MGI:88604

Synonyms

9030605E09Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 15

38.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr15:82555108-82559413 bp, + strand From Ensembl annotation of GRCm38   4306 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:86099  Vertebrate Homology Class
1 human; 5 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2d12

Human homologs

Human Homolog		CYP2D6, cytochrome P450, family 2, subfamily D, polypeptide 6
NCBI Gene ID		1565
neXtProt AC		NX_P10635
Human Synonyms		CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450C2D, P450DB1, P450-DB1
Human Chr (Location)		22q13.1; chr22:42522501-42526883 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CYP2D6

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	oxidation-reduction process
Component	mitochondrion
Function	drug binding, heme binding, ...

External Resources: FuncBase

Expression

cDNA source data(17)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(17) cDNA(17)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000096852 (Evidence)
Entrez Gene	380997 (Evidence)
UniGene	482248
DFCI	TC1585852, TC1608301, TC1611246
DoTS	DT.101280407, DT.101337908, DT.40172359, DT.87078386
NIA Mouse Gene Index	U103554
Consensus CDS Project	CCDS37160.1
International Mouse Knockout Project Status	Cyp2d12

Sequences

Length	Strain/Species
genomic	ENSMUSG00000096852	Ensembl Gene Model | MGI Sequence Detail	4306	C57BL/6J
transcript	ENSMUST00000068861	Ensembl | MGI Sequence Detail	1614	Not Applicable
polypeptide	ENSMUSP00000071064	Ensembl | MGI Sequence Detail	504	Not Applicable

All sequences(23) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(22 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
InterPro	IPR008069	Cytochrome P450, E-class, group I, CYP2D-like

References

(Earliest) J:4152 Nelson DR, et al., The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol. 1993 Jan-Feb;12(1):1-51
(Latest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
All references(19)

Other accession IDs

MGD-MRK-2323, MGI:3584268