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Cyp2d12 Gene Detail
Summary
  • Symbol
    Cyp2d12
  • Name
    cytochrome P450, family 2, subfamily d, polypeptide 12
  • Synonyms
    9030605E09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:88604
    NCBI Gene: 380997
  • Member of
    Cyp2d cluster
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:82555044-82559413 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 38.64 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    37 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88604
protein coding gene Chr15:82555044-82560403 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022150
protein coding gene Chr15:82975644-82980064 (+)
A/J MGP_AJ_G0022109
protein coding gene Chr15:80144597-80148902 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0022115
protein coding gene Chr15:80240359-80244664 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0022559
protein coding gene Chr15:86393298-86397603 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0021406
protein coding gene Chr15:83155926-83161377 (+)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0021958
protein coding gene Chr15:78681353-78685503 (+)
LP/J MGP_LPJ_G0022049
protein coding gene Chr15:83308909-83313220 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021978
protein coding gene Chr15:94038614-94043759 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022574
protein coding gene Chr15:82484232-82488537 (+)
PWK/PhJ MGP_PWKPhJ_G0021147
protein coding gene Chr15:79556316-79559958 (+)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 380997 NCBI Gene Model | MGI Sequence Detail 4370 C57BL/6J ±  kb
transcript NM_201360 RefSeq | MGI Sequence Detail 1633 C57BL/6  
polypeptide NP_958748 RefSeq | MGI Sequence Detail 504 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR001128 Cytochrome P450
    IPR017972 Cytochrome P450, conserved site
    IPR002401 Cytochrome P450, E-class, group I
    IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
    IPR036396 Cytochrome P450 superfamily
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-2323, MGI:3584268
References
more
  • Summaries
    All 32
    Diseases 1
    Gene Ontology 1
    Phenotypes 19
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory