Cyp2d10
Gene Detail

Symbol Name ID

Cyp2d10 cytochrome P450, family 2, subfamily d, polypeptide 10 MGI:88602

Synonyms

Cyp2d, P450-2D

Feature Type

protein coding gene

Genetic Map

Chromosome 15

38.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr15:82402846-82407194 bp, - strand From NCBI annotation of GRCm38   4349 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:86099  Vertebrate Homology Class
1 human; 5 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2d10

Human homologs

Human Homolog		CYP2D6, cytochrome P450, family 2, subfamily D, polypeptide 6
NCBI Gene ID		1565
neXtProt AC		NX_P10635
Human Synonyms		CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450C2D, P450DB1, P450-DB1
Human Chr (Location)		22q13.1; chr22:42522501-42526883 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human CYP2D6

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function	aromatase activity, drug binding, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (146)    Tissues (96)    Images (49)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	146

cDNA source data(203)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(205) Genomic(2) cDNA(203)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000094806 (Evidence)
Entrez Gene	13101 (Evidence)
UniGene	174372
DoTS	DT.55103310, DT.94219381, DT.97378087
NIA Mouse Gene Index	U150625
EC	1.14.14.1
Consensus CDS Project	CCDS27690.1
International Mouse Knockout Project Status	Cyp2d10

Sequences

Length	Strain/Species
genomic	13101	NCBI Gene Model | MGI Sequence Detail	4349	C57BL/6J
transcript	NM_010005	RefSeq | MGI Sequence Detail	1681	Not Specified
polypeptide	P24456	UniProt | EBI | MGI Sequence Detail	504	Not Applicable

All sequences(22) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(136 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
InterPro	IPR008069	Cytochrome P450, E-class, group I, CYP2D-like
Protein Ontology	PR:000006234	cytochrome P450 2D10

Graphical View of Protein Domain Structure

References

(Earliest) J:9597 Wong G, et al., Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16 alpha)) in mice. Organization, differential regulation, and chromosome localization. J Biol Chem. 1989 Feb 15;264(5):2920-7
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Other accession IDs

MGD-MRK-13111, MGD-MRK-2321, MGI:2145967