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Cyp2d10
Gene Detail
 Symbol
Name
ID
Cyp2d10
cytochrome P450, family 2, subfamily d, polypeptide 10
MGI:88602
Synonyms Cyp2d, P450-2D
Feature Type protein coding gene
Genetic Map
Chromosome 15
38.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr15:82402846-82407194 bp, - strand
From NCBI annotation of GRCm38

  4349 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:86099  Vertebrate Homology Class
1 human; 5 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2d10

Human
homologs
Human Homolog CYP2D6, cytochrome P450, family 2, subfamily D, polypeptide 6
NCBI Gene ID 1565
neXtProt AC  NX_P10635
Human Synonyms  CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450C2D, P450DB1, P450-DB1
Human Chr (Location)  22q13.1; chr22:42126499-42130881 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYP2D6
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process oxidation-reduction process
Component endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function aromatase activity, drug binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (146)    Tissues (96)    Images (49)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 146
cDNA source data(203)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(205) Genomic(2) cDNA(203)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000094806 (Evidence)
Entrez Gene13101 (Evidence)
UniGene174372
DoTSDT.55103310, DT.94219381, DT.97378087
NIA Mouse Gene IndexU150625
EC1.14.14.1
Consensus CDS ProjectCCDS27690.1
International Mouse Knockout Project StatusCyp2d10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 13101 NCBI Gene Model | MGI Sequence Detail 4349 C57BL/6J ±  kb
transcript NM_010005 RefSeq | MGI Sequence Detail 1681 Not Specified 
polypeptide P24456 UniProt | EBI | MGI Sequence Detail 504 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(164 from dbSNP Build 137)    SNPs within 2kb including multiple locations(198)
Protein-related
information
ResourceIDDescription
InterPro IPR001128 Cytochrome P450
InterPro IPR017972 Cytochrome P450, conserved site
InterPro IPR002401 Cytochrome P450, E-class, group I
InterPro IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
Protein Ontology PR:000006234 cytochrome P450 2D10
Graphical View of Protein Domain Structure
References (Earliest) J:9597 Wong G, et al., Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16 alpha)) in mice. Organization, differential regulation, and chromosome localization. J Biol Chem. 1989 Feb 15;264(5):2920-7
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)
Other
accession IDs
MGD-MRK-13111, MGD-MRK-2321, MGI:2145967

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory