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Csnk2a2
Gene Detail
 Symbol
Name
ID
Csnk2a2
casein kinase 2, alpha prime polypeptide
MGI:88547
Synonyms 1110035J23Rik, CK2
Feature Type protein coding gene
Genetic Map
Chromosome 8
47.12 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr8:95446096-95488820 bp, - strand
From NCBI annotation of GRCm38

  42725 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20444  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Csnk2a2

Human
homologs
Human Homolog CSNK2A2, casein kinase 2, alpha prime polypeptide
NCBI Gene ID 1459
neXtProt AC  NX_P19784
Human Synonyms  CK2A2, CSNK2A1
Human Chr (Location)  16q21; chr16:58157907-58197878 (-)  GRCh38
Alleles
and
phenotypes
All alleles(13) : Targeted(2) Gene trapped(11)
 
Males homozygotes for a targeted null mutation of the minor catalytic subunit exhibit infertility with oligospermia and abnormally shaped spermatid nuclei.
 
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process apoptotic process, cell cycle, ...
Component nucleus, PcG protein complex, ...
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (142)    Tissues (133)    Images (18)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 142
cDNA source data(20)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(28) Genomic(1) cDNA(22) Primer pair(5)
Microarray probesets(11)
Other database
links
Ensembl Gene ModelENSMUSG00000046707 (Evidence)
Entrez Gene13000 (Evidence)
DFCITC1577971, TC1604034, TC1643470
DoTSDT.101737816, DT.530502
NIA Mouse Gene IndexU030136, U364868
EC2.7.11.1
Consensus CDS ProjectCCDS22562.1
International Mouse Knockout Project StatusCsnk2a2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 13000 NCBI Gene Model | MGI Sequence Detail 42725 C57BL/6J ±  kb
transcript NM_009974 RefSeq | MGI Sequence Detail 3766 C57BL/6 
polypeptide O54833 UniProt | EBI | MGI Sequence Detail 350 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(10) UniProt(4)
Polymorphisms PCR(4) : SNPs within 2kb(246 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000005951 casein kinase II subunit alpha'
Graphical View of Protein Domain Structure
References (Earliest) J:2617 Yang-Feng TL, et al., Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit. Nucleic Acids Res. 1991 Dec;19(25):7125-9
(Latest) J:190725 Iyengar AS, et al., Identification of CK2 as the kinase that phosphorylates Pax3 at Ser209 in early myogenic differentiation. Biochem Biophys Res Commun. 2012 Nov 9;428(1):24-30
All references(59)
Other
accession IDs
MGD-MRK-2205, MGI:1915939, MGI:2142847

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory