Homozygotes for targeted null mutations exhibit impaired blood vessel development, retarded growth, and, in most cases, midgestational lethality. On a mixed background, some mutants survive to birth and appear to be normal.
|Process||activation of cysteine-type endopeptidase activity involved in apoptotic process, activation of plasma proteins involved in acute inflammatory response, ...|
|Component||cell surface, cytoplasm, ...|
|Function||cytokine receptor activity, phospholipid binding, ...|
|InterPro||IPR003961||Fibronectin, type III|
|InterPro||IPR015373||Interferon alpha/beta receptor, beta chain|
|InterPro||IPR016354||Tissue factor/coagulation factor III|
|Protein Ontology||PR:000001940||tissue factor|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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