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Cebpb
Gene Detail
 Symbol
Name
ID
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
MGI:88373
Synonyms C/EBPbeta, C/EBP BETA, CRP2, IL-6DBP, LAP, LIP, Nfil6, NF-IL6, NF-M
Feature Type protein coding gene
Genetic Map
Chromosome 2
87.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(9)
Sequence Map
Chr2:167688915-167690418 bp, + strand
From VEGA annotation of GRCm38

  1504 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3807  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken

Protein SuperFamily: CCAAT/enhancer-binding protein
Gene Tree: Cebpb

Human
homologs
Human Homolog CEBPB, CCAAT/enhancer binding protein (C/EBP), beta
NCBI Gene ID 1051
neXtProt AC  NX_P17676
Human Synonyms  C/EBP-beta, CRP2, IL6DBP, NF-IL6, TCF5
Human Chr (Location)  20q13.1; chr20:50190583-50192690 (+)  GRCh38
Alleles
and
phenotypes
All alleles(12) : Targeted(12)
 
Homozygotes for targeted null mutations exhibit high neonatal hypoglycemia and mortality, reduced epididymal fat pad weight, susceptibility to Listeria monocytogenes, female sterility, impaired mammary development, and resistance to skin carcinogenesis.
 
Phenotype Images(3)
Gene Ontology
(GO)
classifications
All GO classifications: (61 annotations)
Process brown fat cell differentiation, cell differentiation, ...
Component condensed chromosome, centromeric region, cytoplasm, ...
Function chromatin binding, DNA binding, ...
External Resources: FuncBase
Expression
Literature Summary: (37 records)
Data Summary: Results (199)    Tissues (139)    Images (20)
Theiler Stages: 11, 13, 14, 15, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
Immunohistochemistry 2
RNA in situ 140
Northern blot 34
Western blot 12
RT-PCR 11
cDNA source data(50)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(63) Genomic(4) cDNA(54) Primer pair(4) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000016307 (Evidence)
Ensembl Gene ModelENSMUSG00000056501 (Evidence)
Entrez Gene12608 (Evidence)
UniGene439656
DFCITC1581829
DoTSDT.486837, DT.97359798
NIA Mouse Gene IndexU002854
PDB1CI6
Consensus CDS ProjectCCDS17105.1
International Mouse Knockout Project StatusCebpb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016307 VEGA Gene Model | MGI Sequence Detail 1504 C57BL/6J ±  kb
transcript OTTMUST00000039186 VEGA | MGI Sequence Detail 1504 Not Applicable 
polypeptide OTTMUSP00000017503 VEGA | MGI Sequence Detail 296 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(6) UniProt(3)
Polymorphisms RFLP(2) : SNPs within 2kb(0 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004827 Basic-leucine zipper domain
InterPro IPR016468 CCAAT/enhancer-binding
Protein Ontology PR:000005308 CCAAT/enhancer-binding protein beta
References (Earliest) J:27206 Chang CJ, et al., Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family. Mol Cell Biol. 1990 Dec;10(12):6642-53
(Latest) J:206241 Cain DW, et al., Identification of a tissue-specific, C/EBPbeta-dependent pathway of differentiation for murine peritoneal macrophages. J Immunol. 2013 Nov 1;191(9):4665-75
All references(244)
Other
accession IDs
MGD-MRK-12827, MGD-MRK-1917, MGI:97310

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory