Cd24a
Gene Detail

Symbol Name ID

Cd24a CD24a antigen MGI:88323

STS

D10Mit107

Synonyms

cluster of differentiation 24, heat stable antigen, HSA, Ly-52, nectadrin

Feature Type

protein coding gene

Genetic Map

Chromosome 10

23.01 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)

Sequence Map

Chr10:43579169-43584262 bp, + strand From Ensembl annotation of GRCm38   5094 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:7662  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Gene Tree: Cd24a

Alleles and phenotypes

All alleles(10) : Targeted(3) Gene trapped(7)
 

Homozygous mutation of this gene results in slight impairment of B cell development. Mutant erythrocytes have increased tendency to aggregate.

 

Gene Ontology (GO) classifications

All GO classifications: (75 annotations)

Process	apoptotic mitochondrial changes, apoptotic nuclear changes, ...
Component	anchored to external side of plasma membrane, anchored to membrane, ...
Function	carbohydrate binding, eukaryotic cell surface binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (19 records)
Data Summary: Results (84)    Tissues (72)    Images (7)
Theiler Stages: 11, 13, 18, 19, 20, 21, 22, 23, 24, 26, 28

Assay Type	Results
Immunohistochemistry	9
RNA in situ	71
RT-PCR	4

cDNA source data(431)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(438) Genomic(2) cDNA(434) Primer pair(1) Other(1)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000047139 (Evidence)
Entrez Gene	12484 (Evidence)
UniGene	29742
DFCI	TC1573745
DoTS	DT.101167066, DT.55107414, DT.91442458
NIA Mouse Gene Index	U015980, U114188
Consensus CDS Project	CCDS23821.1
International Mouse Knockout Project Status	Cd24a

Sequences

Length	Strain/Species
genomic	ENSMUSG00000047139	Ensembl Gene Model | MGI Sequence Detail	5094	C57BL/6J
transcript	ENSMUST00000058714	Ensembl | MGI Sequence Detail	1813	Not Applicable
polypeptide	ENSMUSP00000057983	Ensembl | MGI Sequence Detail	76	Not Applicable

All sequences(29) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(2) : SNPs(66 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000001932	signal transducer CD24

References

(Earliest) J:10697 Kay R, et al., Expression cloning of a cDNA encoding M1/69-J11d heat-stable antigens. J Immunol. 1990 Sep 15;145(6):1952-9
(Latest) J:193456 Chen W, et al., Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation. Cell. 2013 Jan 31;152(3):467-78
All references(123)

Other accession IDs

MGD-MRK-11995, MGD-MRK-1840