About   Help   FAQ
Cd24a Gene Detail
Summary
  • Symbol
    Cd24a
  • Name
    CD24a antigen
  • Synonyms
    cluster of differentiation 24, heat stable antigen, HSA, Ly-52, nectadrin
  • Feature Type
    protein coding gene
  • IDs
    MGI:88323
    NCBI Gene: 12484
  • Gene Overview
    MyGene.info: CD24
Location & Maps
more
  • Sequence Map
    Chr10:43579169-43584262 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5094 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 23.01 cM
  • Mapping Data
    4 experiments
  • Sequence Tag
Homology
more
  • Human Ortholog
    CD24, CD24 molecule
  • Human Ortholog
    CD24, CD24 molecule
    Orthology source: HGNC
  • Synonyms
    CD24A
  • Links
    NCBI Gene ID: 100133941
    neXtProt AC: NX_P25063

  • Chr Location
    chr6:106969831-106976855 (-)  GRCh38.p2

  • HCOP
    human homology predictions: CD24
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    33 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    7
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Cd24a
Homozygous mutation of this gene results in slight impairment of B cell development. Mutant erythrocytes have increased tendency to aggregate.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047139 Ensembl Gene Model | MGI Sequence Detail 5094 C57BL/6J ±  kb
transcript ENSMUST00000058714 Ensembl | MGI Sequence Detail 1813 Not Applicable  
polypeptide ENSMUSP00000057983 Ensembl | MGI Sequence Detail 76 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    74 from dbSNP Build 142
  • RFLP
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000001932 signal transducer CD24
  • InterPro Domains
    IPR028029 Signal transducer CD24
Molecular
Reagents
less
  • All nucleic 465
    Genomic 2
    cDNA 461
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-11995, MGD-MRK-1840
References
more
  • Summaries
    All 128
    Developmental Gene Expression 24
    Gene Ontology 62
    Phenotypes 33
  • Earliest
    J:10697 Kay R, et al., Expression cloning of a cDNA encoding M1/69-J11d heat-stable antigens. J Immunol. 1990 Sep 15;145(6):1952-9
  • Latest
    J:226960 Cuevas E, et al., Lin41/Trim71 is essential for mouse development and specifically expressed in postnatal ependymal cells of the brain. Front Cell Dev Biol. 2015;3:20

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/20/2016
MGI 6.05
The Jackson Laboratory