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Bsg
Gene Detail
 Symbol
Name
ID
Bsg
basigin
MGI:88208
Synonyms 5A11/Basigin, CD147, EMMPRIN, gp 42, HT-7, neurothelin
Feature Type protein coding gene
Genetic Map
Chromosome 10
39.72 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)
Sequence Map
Chr10:79704491-79711969 bp, + strand
From VEGA annotation of GRCm38

  7479 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1308  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 chicken; 1 zebrafish

Protein SuperFamily: cell surface glycoprotein HT7
Gene Tree: Bsg

Human
homologs
Human Homolog BSG, basigin (Ok blood group)
NCBI Gene ID 682
neXtProt AC  NX_P35613
Human Synonyms  5F7, CD147, EMMPRIN, M6, OK, TCSF
Human Chr (Location)  19p13.3; chr19:571277-583493 (+)  GRCh38
Alleles
and
phenotypes
All alleles(5) : Gene trapped(3) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Most homozygous null mutants die near the time of implantation. Half of the survivors die prior to 1 month of age from interstitial pneumonia. The remaining mice are small, sterile, have retinal abnormalities, and perform poorly in behavioral tests.
 
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process protein targeting to plasma membrane
Component acrosomal membrane, extracellular vesicular exosome, ...
Function mannose binding
External Resources: FuncBase
Expression
Literature Summary: (12 records)
Data Summary: Results (213)    Tissues (111)   
Theiler Stages: 1, 2, 3, 4, 5, 6, 17, 19, 21, 22, 28
Assay TypeResults
Immunohistochemistry 5
RNA in situ 175
Northern blot 17
RT-PCR 16
cDNA source data(494)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(501) Genomic(3) cDNA(494) Primer pair(4)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000042290 (Evidence)
Ensembl Gene ModelENSMUSG00000023175 (Evidence)
Entrez Gene12215 (Evidence)
UniGene726
DFCITC1573844, TC1586331
DoTSDT.101165451, DT.101361365, DT.101361655, DT.101361743, DT.103586418, DT.110628685, DT.110628768, DT.110628911, DT.110628916, DT.110629031, DT.110629784, DT.110629862, DT.496444, DT.91569286, DT.97415679, DT.97415682
NIA Mouse Gene IndexU011720
Consensus CDS ProjectCCDS23985.1, CCDS35967.1
International Mouse Knockout Project StatusBsg
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000042290 VEGA Gene Model | MGI Sequence Detail 7479 C57BL/6J ±  kb
transcript OTTMUST00000111260 VEGA | MGI Sequence Detail 1526 Not Applicable 
polypeptide OTTMUSP00000062228 VEGA | MGI Sequence Detail 389 Not Applicable 

For the selected sequences
All sequences(79) RefSeq(4) UniProt(5)
Polymorphisms RFLP(5) : SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009151 Basigin
InterPro IPR013098 Immunoglobulin I-set
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR003598 Immunoglobulin subtype 2
Protein Ontology PR:000001324 basigin
References (Earliest) J:10365 Altruda F, et al., Cloning of cDNA for a novel mouse membrane glycoprotein (gp42): shared identity to histocompatibility antigens, immunoglobulins and neural-cell adhesion molecules. Gene. 1989 Dec 28;85(2):445-51
(Latest) J:199573 Bi J, et al., Basigin null mutant male mice are sterile and exhibit impaired interactions between germ cells and Sertoli cells. Dev Biol. 2013 Aug 15;380(2):145-56
All references(81)
Other
accession IDs
MGD-MRK-1674, MGI:2143523, MGI:2143580

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory