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Bglap3 Gene Detail
Summary
  • Symbol
    Bglap3
  • Name
    bone gamma-carboxyglutamate protein 3
  • Synonyms
    Bglap-rs1, mOC-X, ORG
  • Feature Type
    protein coding gene
  • IDs
    MGI:88155
    NCBI Gene: 12095
  • Gene Overview
    MyGene.info: BGLAP
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:88368616-88372741 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 38.81 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88155
protein coding gene Chr3:88368616-88372743 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0027366
protein coding gene Chr3:85628308-85631377 (-)
C3H/HeJ MGP_C3HHeJ_G0027109
protein coding gene Chr3:87910587-87912281 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027812
protein coding gene Chr3:91809203-91824765 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025165
protein coding gene Chr3:81145375-81146331 (-)
CAST/EiJ MGP_CASTEiJ_G0026555
protein coding gene Chr3:88151896-88152862 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0027208
protein coding gene Chr3:101154600-101155430 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027870
protein coding gene Chr3:87386116-87387671 (-)
PWK/PhJ MGP_PWKPhJ_G0026288
protein coding gene Chr3:84813658-84814522 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026106
protein coding gene Chr3:86576465-86582800 (-)
WSB/EiJ MGP_WSBEiJ_G0026635
protein coding gene Chr3:87754524-87756128 (-)



Homology
more
  • Human Ortholog
    BGLAP, bone gamma-carboxyglutamate protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BGLAP, bone gamma-carboxyglutamate protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BGP, OC, OCN
  • Links
    NCBI Gene ID: 632
    neXtProt AC: NX_P02818
    UniProt: P02818

  • Chr Location
    1q22; chr1:156241962-156243332 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Bglap3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12095 NCBI Gene Model | MGI Sequence Detail 4126 C57BL/6J ±  kb
transcript NM_001305448 RefSeq | MGI Sequence Detail 1045 C57BL/6  
polypeptide P54615 UniProt | EBI | MGI Sequence Detail 95 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    Genomic 4
    cDNA 41
    Primer pair 1
    Other 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-1551, MGI:2139729
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:16166 Rahman S, et al., Multiple copies of the bone-specific osteocalcin gene in mouse and rat. Endocrinology. 1993 Dec;133(6):3050-3
  • Latest
    J:256083 Yang T, et al., Pten regulates neural crest proliferation and differentiation during mouse craniofacial development. Dev Dyn. 2018 Feb;247(2):304-314

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory