About   Help   FAQ
Apoc3
Gene Detail
 Symbol
Name
ID
Apoc3
apolipoprotein C-III
MGI:88055
STS D9Mit93
Feature Type protein coding gene
Genetic Map
Chromosome 9
25.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr9:46232933-46235636 bp, - strand
From VEGA annotation of GRCm38

  2704 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:136634  Vertebrate Homology Class
1 mouse; 1 rat

Gene Tree: Apoc3

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(1) Targeted(6)
 
Homozygotes for a targeted null mutation exhibit reduced fasted triglyceride levels, increased triglyceride secretion rate, and loss of postprandial and obesity-associated hypertriglyceridemia.
 
Interactions
Apoc3 interacts with 37 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (22 annotations)
Process cellular response to glucose stimulus, cholesterol metabolic process, ...
Component cell, chylomicron, ...
Function lipid binding
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (4 records)
cDNA source data(149)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(152) Genomic(3) cDNA(149)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000028703 (Evidence)
Ensembl Gene ModelENSMUSG00000032081 (Evidence)
Entrez Gene11814 (Evidence)
UniGene390161
DFCITC1577035, TC1705967
DoTSDT.91338974, DT.94194339
Consensus CDS ProjectCCDS23141.1
International Mouse Knockout Project StatusApoc3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028703 VEGA Gene Model | MGI Sequence Detail 2704 C57BL/6J ±  kb
transcript OTTMUST00000071086 VEGA | MGI Sequence Detail 709 Not Applicable 
polypeptide OTTMUSP00000036350 VEGA | MGI Sequence Detail 137 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(90 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008403 Apolipoprotein CIII
Protein Ontology PR:000004152 apolipoprotein C-III
References (Earliest) J:6686 Kratochvilova J, Dominant cataract mutations detected in offspring of gamma-irradiated male mice. J Hered. 1981 Sep-Oct;72(5):302-7
(Latest) J:208341 Seth A, et al., Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment. Development. 2014 Feb;141(3):538-47
All references(56)
Other
accession IDs
MGD-MRK-1371, MGD-MRK-1374

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory