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Apoc2
Gene Detail
 Symbol
Name
ID
Apoc2
apolipoprotein C-II
MGI:88054
Feature Type protein coding gene
Genetic Map
Chromosome 7
9.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr7:19671584-19681423 bp, - strand
From VEGA annotation of GRCm38

  9840 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:47928  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog

Gene Tree: Apoc2

Human
homologs
Human Homolog APOC2, apolipoprotein C-II
NCBI Gene ID 344
neXtProt AC  NX_P02655
Human Synonyms  APO-CII, APOC-II
Human Chr (Location)  19q13.2; chr19:44945982-44949565 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human APOC2
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(5)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Apoc2 interacts with 23 markers (Mir30c-1, Mir30c-2, Mir125a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (37 annotations)
Process cholesterol efflux, chylomicron remnant clearance, ...
Component chylomicron, extracellular region, ...
Function enzyme activator activity, lipase inhibitor activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (14 records)
Data Summary: Results (76)    Tissues (38)    Images (36)
Theiler Stages: 12, 13, 19, 20, 23, 28
Assay TypeResults
RNA in situ 62
Northern blot 9
RT-PCR 5
cDNA source data(101)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(109) Genomic(1) cDNA(101) Primer pair(5) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000032974 (Evidence)
Ensembl Gene ModelENSMUSG00000002992 (Evidence)
Entrez Gene11813 (Evidence)
UniGene28394
DFCITC1578629
DoTSDT.496045
Consensus CDS ProjectCCDS39801.1
International Mouse Knockout Project StatusApoc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032974 VEGA Gene Model | MGI Sequence Detail 9840 C57BL/6J ±  kb
transcript OTTMUST00000082222 VEGA | MGI Sequence Detail 569 Not Applicable 
polypeptide OTTMUSP00000044050 VEGA | MGI Sequence Detail 97 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(108 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023121 ApoC-II domain
InterPro IPR008019 Apolipoprotein C-II
Protein Ontology PR:000004151 apolipoprotein C-II
References (Earliest) J:24996 Mahley RW, et al., Plasma lipoproteins: apolipoprotein structure and function. J Lipid Res. 1984 Dec 1;25(12):1277-94
(Latest) J:208341 Seth A, et al., Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment. Development. 2014 Feb;141(3):538-47
All references(49)
Other
accession IDs
MGD-MRK-1373

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory