Apoc2
Gene Detail

Symbol Name ID

Apoc2 apolipoprotein C-II MGI:88054

Feature Type

protein coding gene

Genetic Map

Chromosome 7

9.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)

Sequence Map

Chr7:19671584-19681423 bp, - strand From VEGA annotation of GRCm38   9840 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:47928  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 dog

Gene Tree: Apoc2

Human homologs

Human Homolog		APOC2, apolipoprotein C-II
NCBI Gene ID		344
neXtProt AC		NX_P02655
Human Synonyms		APO-CII, APOC-II
Human Chr (Location)		19q13.2; chr19:45449239-45452822 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human APOC2

Alleles and phenotypes

All alleles(5) : Gene trapped(5)

Gene Ontology (GO) classifications

All GO classifications: (36 annotations)

Process	cholesterol efflux, chylomicron remnant clearance, ...
Component	chylomicron, extracellular region, ...
Function	enzyme activator activity, lipase inhibitor activity, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (13 records)
Data Summary: Results (76)    Tissues (38)    Images (36)
Theiler Stages: 12, 13, 19, 20, 23, 28

Assay Type	Results
RNA in situ	62
Northern blot	9
RT-PCR	5

cDNA source data(101)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(109) Genomic(1) cDNA(101) Primer pair(5) Other(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000032974 (Evidence)
Ensembl Gene Model	ENSMUSG00000002992 (Evidence)
Entrez Gene	11813 (Evidence)
UniGene	28394
DFCI	TC1578629
DoTS	DT.496045
Consensus CDS Project	CCDS39801.1
International Mouse Knockout Project Status	Apoc2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000032974	VEGA Gene Model | MGI Sequence Detail	9840	C57BL/6J
transcript	OTTMUST00000082222	VEGA | MGI Sequence Detail	569	Not Applicable
polypeptide	OTTMUSP00000044050	VEGA | MGI Sequence Detail	97	Not Applicable

All sequences(39) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(39 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR023121	ApoC-II domain
InterPro	IPR008019	Apolipoprotein C-II
Protein Ontology	PR:000004151	apolipoprotein C-II

References

(Earliest) J:24996 Mahley RW, et al., Plasma lipoproteins: apolipoprotein structure and function. J Lipid Res. 1984 Dec 1;25(12):1277-94
(Latest) J:184721 Viotti M, et al., Role of the gut endoderm in relaying left-right patterning in mice. PLoS Biol. 2012 Mar;10(3):e1001276
All references(48)

Other accession IDs

MGD-MRK-1373