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Apoc2
Gene Detail
Symbol

Name
ID
Apoc2
apolipoprotein C-II
MGI:88054
Feature Type
protein coding gene
Genetic Map
Chromosome 7
9.94 cM
Detailed Genetic Map ± 1 cM


Mapping data(6)
Sequence Map
Chr7:19671584-19681423 bp, - strand
From VEGA annotation of GRCm38

  9840 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:47928  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: APOC2
Gene Tree: Apoc2

Human
homologs
APOC2, apolipoprotein C-II
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 344
neXtProt AC: NX_P02655

Human Synonyms: APO-CII, APOC-II

Human Chr (Location): 19q13.2; chr19:44945982-44949565 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human APOC2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(5) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Apoc2 interacts with 23 markers (Mir30c-1, Mir30c-2, Mir125a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (38 annotations)
Process cholesterol efflux, chylomicron remnant clearance, ...
Component chylomicron, extracellular exosome, ...
Function enzyme activator activity, lipase inhibitor activity, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (15 records)
Data Summary: Results (76)    Tissues (38)    Images (36)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 62
Northern blot 9
RT-PCR 5
cDNA source data(101)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(109) Genomic(1) cDNA(101) Primer pair(5) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000032974 (Evidence)
Ensembl Gene Model ENSMUSG00000002992 (Evidence)
Entrez Gene 11813 (Evidence)
UniGene 28394
DFCI TC1578629
DoTS DT.496045
Consensus CDS Project CCDS39801.1
International Mouse Phenotyping Consortium Status Apoc2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032974 VEGA Gene Model | MGI Sequence Detail 9840 C57BL/6J ±  kb
transcript OTTMUST00000082223 VEGA | MGI Sequence Detail 589 Not Applicable 
polypeptide OTTMUSP00000044051 VEGA | MGI Sequence Detail 97 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(108 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023121 ApoC-II domain
InterPro IPR008019 Apolipoprotein C-II
Protein Ontology PR:000004151 apolipoprotein C-II
References
(Earliest) J:24996 Mahley RW, et al., Plasma lipoproteins: apolipoprotein structure and function. J Lipid Res. 1984 Dec 1;25(12):1277-94
(Latest) J:214986 Walker EM, et al., GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94
All references(47)
Other
accession IDs
MGD-MRK-1373

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory