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Aldoa
Gene Detail
 Symbol
Name
ID
Aldoa
aldolase A, fructose-bisphosphate
MGI:87994
Synonyms Aldo1, Aldo-1
Feature Type protein coding gene
Genetic Map
Chromosome 7
69.25 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:126795234-126800751 bp, - strand
From VEGA annotation of GRCm38

  5518 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:123896  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: fructose-bisphosphate aldolase
Gene Tree: Aldoa

Human
homologs
Human Homolog ALDOA, aldolase A, fructose-bisphosphate
NCBI Gene ID 226
neXtProt AC  NX_P04075
Human Synonyms  ALDA, GSD12, HEL-S-87p
Human Chr (Location)  16p11.2; chr16:30053090-30070420 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human ALDOA
Mutations,
alleles, and
phenotypes
All mutations/alleles(32) : Gene trapped(28) Targeted(4)
Genomic Mutations involving Aldoa (2)
Incidental mutations (data from APF )
Alleles Annotated to Human Diseases(1)   
Interactions
Aldoa interacts with 48 markers (Mir1b, Mir15a, Mir27a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process ATP biosynthetic process, fructose 1,6-bisphosphate metabolic process, ...
Component actin cytoskeleton, cytoplasm, ...
Function cytoskeletal protein binding, fructose binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (9 records)
Data Summary: Results (212)    Tissues (148)    Images (35)
Theiler Stages: 22, 23, 24, 26, 27, 28
Assay TypeResults
RNA in situ 176
RNase protection 36
cDNA source data(1042)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(1046) Genomic(2) cDNA(1042) Primer pair(1) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000025167 (Evidence)
Ensembl Gene ModelENSMUSG00000030695 (Evidence)
Entrez Gene11674 (Evidence)
UniGene275831
Consensus CDS ProjectCCDS21845.1, CCDS52399.1
International Mouse Knockout Project StatusAldoa
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025167 VEGA Gene Model | MGI Sequence Detail 5518 C57BL/6J ±  kb
transcript OTTMUST00000061918 VEGA | MGI Sequence Detail 1549 Not Applicable 
polypeptide OTTMUSP00000030465 VEGA | MGI Sequence Detail 418 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(12)
Polymorphisms SNPs within 2kb(9 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000003934 fructose-bisphosphate aldolase A
References (Earliest) J:21434 Paolella G, et al., Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A. Eur J Biochem. 1986 Apr 15;156(2):229-35
(Latest) J:178379 Richard AF, et al., Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20
All references(50)
Other
accession IDs
MGD-MRK-1276, MGD-MRK-1278

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory