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Aldoa
Gene Detail
Symbol

Name
ID
Aldoa
aldolase A, fructose-bisphosphate
MGI:87994
Synonyms
Aldo1, Aldo-1
Feature Type
protein coding gene
Genetic Map
Chromosome 7
69.25 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:126795234-126800751 bp, - strand
From VEGA annotation of GRCm38

  5518 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:123896  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: ALDOA
Protein SuperFamily: fructose-bisphosphate aldolase
Gene Tree: Aldoa

Human
homologs
ALDOA, aldolase A, fructose-bisphosphate
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 226
neXtProt AC: NX_P04075

Human Synonyms: ALDA, GSD12, HEL-S-87p

Human Chr (Location): 16p11.2; chr16:30053090-30070420 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ALDOA

Mutations,
alleles, and
phenotypes
All mutations/alleles(34) : Gene trapped(28) Targeted(6)
Genomic Mutations involving Aldoa (3)
Incidental mutations (data from APF )
Mutations Annotated to Human Diseases (2)   
Interactions
Aldoa interacts with 48 markers (Mir1b, Mir15a, Mir27a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process ATP biosynthetic process, fructose 1,6-bisphosphate metabolic process, ...
Component actin cytoskeleton, cytoplasm, ...
Function cytoskeletal protein binding, fructose binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (212)    Tissues (148)    Images (35)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 176
RNase protection 36
cDNA source data(1042)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase aldoa ; ZFIN aldoab    NEW 
Molecular
reagents
All nucleic(1046) Genomic(2) cDNA(1042) Primer pair(1) Other(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000025167 (Evidence)
Ensembl Gene Model ENSMUSG00000030695 (Evidence)
Entrez Gene 11674 (Evidence)
UniGene 275831
Consensus CDS Project CCDS21845.1, CCDS52399.1
International Mouse Phenotyping Consortium Status Aldoa
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025167 VEGA Gene Model | MGI Sequence Detail 5518 C57BL/6J ±  kb
transcript OTTMUST00000061918 VEGA | MGI Sequence Detail 1549 Not Applicable 
polypeptide OTTMUSP00000030465 VEGA | MGI Sequence Detail 418 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(15)
Polymorphisms
SNPs within 2kb(9 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000003934 fructose-bisphosphate aldolase A
References
(Earliest) J:21434 Paolella G, et al., Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A. Eur J Biochem. 1986 Apr 15;156(2):229-35
(Latest) J:216294 Kumar A, et al., Analysis of Presenilin 1 and 2 interacting proteins in mouse cerebral cortex during development. Int J Dev Neurosci. 2014 Nov;38:138-46
All references(52)
Other
accession IDs
MGD-MRK-1276, MGD-MRK-1278

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory