Aldoa
Gene Detail

Symbol Name ID

Aldoa aldolase A, fructose-bisphosphate MGI:87994

Synonyms

Aldo1, Aldo-1

Feature Type

protein coding gene

Genetic Map

Chromosome 7

69.25 cM, cytoband F4
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr7:126795234-126800751 bp, - strand From VEGA annotation of GRCm38   5518 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:123896  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Protein SuperFamily: fructose-bisphosphate aldolase
Gene Tree: Aldoa

Human homologs

Human Homolog		ALDOA, aldolase A, fructose-bisphosphate
NCBI Gene ID		226
neXtProt AC		NX_P04075
Human Synonyms		ALDA, GSD12
Human Chr (Location)		16p11.2; chr16:30064411-30081741 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ALDOA

Alleles and phenotypes

All alleles(30) : Targeted(2) Gene trapped(28)

Gene Ontology (GO) classifications

All GO classifications: (17 annotations)

Process	ATP biosynthetic process, fructose 1,6-bisphosphate metabolic process, ...
Component	actin cytoskeleton, cilium, ...
Function	cytoskeletal protein binding, fructose binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (8 records)
Data Summary: Results (130)    Tissues (101)    Images (22)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	130

cDNA source data(1038)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(1039) cDNA(1038) Primer pair(1)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000025167 (Evidence)
Ensembl Gene Model	ENSMUSG00000030695 (Evidence)
Entrez Gene	11674 (Evidence)
UniGene	275831
Consensus CDS Project	CCDS21845.1, CCDS52399.1
International Mouse Knockout Project Status	Aldoa

Sequences

Length	Strain/Species
genomic	OTTMUSG00000025167	VEGA Gene Model | MGI Sequence Detail	5518	C57BL/6J
transcript	OTTMUST00000061918	VEGA | MGI Sequence Detail	1549	Not Applicable
polypeptide	OTTMUSP00000030465	VEGA | MGI Sequence Detail	418	Not Applicable

All sequences(67) RefSeq(6)

Polymorphisms

SNPs(3 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000003934	fructose-bisphosphate aldolase A

References

(Earliest) J:21434 Paolella G, et al., Structure and expression of mouse aldolase genes. Brain-specific aldolase C amino acid sequence is closely related to aldolase A. Eur J Biochem. 1986 Apr 15;156(2):229-35
(Latest) J:178379 Richard AF, et al., Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20
All references(48)

Other accession IDs

MGD-MRK-1276, MGD-MRK-1278