adducin 1 (alpha)
Targeted gene deletion leads to reduced growth and compensated hemolytic anemia. RBCs are osmotically fragile, dehydrated, and spherocytic with severe loss of membrane surface area and reduced MCV. ~50% of homozygotes develop lethal hydrocephaly with dilation of the lateral, 3rd, and 4th ventricles.
|VEGA Gene Model||OTTMUSG00000023097 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000029106 (Evidence)|
|Entrez Gene||11518 (Evidence)|
|DFCI||TC1572146, TC1584400, TC1600717, TC1609311|
|DoTS||DT.101178210, DT.110643348, DT.110643366, DT.110643394, DT.94373286, DT.94394184, DT.99862613|
|NIA Mouse Gene Index||U005490|
|Consensus CDS Project||CCDS19216.1, CCDS39069.1, CCDS51471.1|
|International Mouse Knockout Project Status||Add1|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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