Mice homozygous for disruption of this gene show a reduction in calcium uptake and transport in cardiomyocytes as well as mild functional abnormalities in the left ventricle. Mice homozygous for a conditional allele activated in collecting ducts exhibit decreased urine osmilality.
|Process||adenylate cyclase-activating G-protein coupled receptor signaling pathway, adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway, ...|
|Component||cell projection, cilium, ...|
|Function||adenylate cyclase activity, ATP binding, ...|
|InterPro||IPR009398||Adenylate cyclase, conserved domain|
|InterPro||IPR001054||Adenylyl cyclase class-3/4/guanylyl cyclase|
|InterPro||IPR018297||Adenylyl cyclase class-4/guanylyl cyclase, conserved site|
|Protein Ontology||PR:000003757||adenylate cyclase type 6|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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