Adcy6 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adcy6
adenylate cyclase 6
MGI:87917

15 phenotypes from 5 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adcy6^{tm1.1(KOMP)Vlcg}/Adcy6^{tm1.1(KOMP)Vlcg} C57BL/6N-Adcy6^{tm1.1(KOMP)Vlcg}/Ucd	increased blood urea nitrogen level	J:211773
	increased circulating alkaline phosphatase level	J:211773
Adcy6^tm1.1Dek/Adcy6^tm1.1Dek Tg(Aqp2-cre)1Dek/0 involves: 129X1/SvJ * C57BL/6 * SJL	decreased urine osmolality	J:180012
Adcy6^tm1Hkh/Adcy6^tm1Hkh involves: 129S1/Sv * 129X1/SvJ	abnormal calcium ion homeostasis	J:143138
	abnormal heart left ventricle pressure	J:143138
	decreased ventricle muscle contractility	J:143138
Adcy6^tm1Yich/Adcy6^tm1Yich involves: 129S6/SvEvTac	abnormal renal water reabsorption	J:161317
	decreased creatinine clearance	J:161317
	decreased urine chloride ion level	J:161317
	decreased urine osmolality	J:161317
	decreased urine potassium level	J:161317
	decreased urine sodium level	J:161317
	decreased urine urea nitrogen level	J:161317
	increased fluid intake	J:161317
	polyuria	J:161317
Adcy6^tm2Yich/Adcy6^tm2Yich involves: 129S6/SvEvTac	abnormal renal water reabsorption	J:161317
	decreased urine chloride ion level	J:161317
	decreased urine creatinine level	J:161317
	decreased urine osmolality	J:161317
	decreased urine potassium level	J:161317
	decreased urine sodium level	J:161317
	decreased urine urea nitrogen level	J:161317
	increased fluid intake	J:161317
	polyuria	J:161317

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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