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Chrnd
Gene Detail
Symbol

Name
ID
Chrnd
cholinergic receptor, nicotinic, delta polypeptide
MGI:87893
Synonyms
Achr-4, Acrd
Feature Type
protein coding gene
Genetic Map
Chromosome 1
44.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(12)
Sequence Map
Chr1:87190607-87200070 bp, + strand
From VEGA annotation of GRCm38

  9464 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37340  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: CHRND
Gene Tree: Chrnd

Human
homologs
CHRND, cholinergic receptor, nicotinic, delta (muscle)
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 1144
neXtProt AC: NX_Q07001

Human Synonyms: ACHRD, CMS2A, CMS3A, CMS3B, CMS3C, FCCMS, SCCMS

Human Chr (Location): 2q37.1; chr2:232526160-232536665 (+)  GRCh38.p2

Disease Associations: (4) Diseases Associated with Human CHRND

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(2) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Chrnd interacts with 148 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (19 records)
Data Summary: Results (51)    Tissues (8)    Images (25)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 12
RNA in situ 30
Northern blot 9
cDNA source data(12)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase chrnd ; ZFIN chrnd    NEW 
Molecular
reagents
All nucleic(24) Genomic(7) cDNA(15) Other(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000048192 (Evidence)
Ensembl Gene Model ENSMUSG00000026251 (Evidence)
Entrez Gene 11447 (Evidence)
UniGene 2811
DFCI TC1589939, TC1607499
DoTS DT.481890, DT.97363109
NIA Mouse Gene Index U000552
Consensus CDS Project CCDS15129.1
International Mouse Phenotyping Consortium Status Chrnd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000048192 VEGA Gene Model | MGI Sequence Detail 9464 C57BL/6J ±  kb
transcript OTTMUST00000123729 VEGA | MGI Sequence Detail 2925 Not Applicable 
polypeptide OTTMUSP00000067484 VEGA | MGI Sequence Detail 520 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(4)
Polymorphisms
RFLP(3) : SNPs within 2kb(55 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006201 Neurotransmitter-gated ion-channel
InterPro IPR018000 Neurotransmitter-gated ion-channel, conserved site
InterPro IPR006202 Neurotransmitter-gated ion-channel ligand-binding
InterPro IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
InterPro IPR027361 Nicotinic acetylcholine-gated receptor, transmembrane domain
InterPro IPR002394 Nicotinic acetylcholine receptor
Protein Ontology PR:000005466 acetylcholine receptor subunit delta
References
(Earliest) J:7701 LaPolla RJ, et al., Isolation and characterization of a cDNA clone for the complete protein coding region of the delta subunit of the mouse acetylcholine receptor. Proc Natl Acad Sci U S A. 1984 Dec;81(24):7970-4
(Latest) J:198597 Gupta S, et al., Function of interfacial prolines at the transmitter-binding sites of the neuromuscular acetylcholine receptor. J Biol Chem. 2013 May 3;288(18):12667-79
All references(77)
Other
accession IDs
MGD-MRK-1039, MGD-MRK-1068, MGI:2138724

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory