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Dnaaf3
Gene Detail
Symbol

Name
ID
Dnaaf3
dynein, axonemal assembly factor 3
MGI:3588207
Synonyms
6030429G01Rik, b2b1739Clo
Feature Type
protein coding gene
Genetic Map
Chromosome 7
2.61 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:4522933-4532453 bp, - strand
From VEGA annotation of GRCm38

  9521 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 2 zebrafish

HCOP human homology predictions: DNAAF3
Gene Tree: Dnaaf3

Human
homologs
DNAAF3, dynein, axonemal, assembly factor 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 352909
neXtProt AC: NX_Q8N9W5

Human Synonyms: C19orf51, CILD2, DAB1, PCD, PF22

Human Chr (Location): 19q13.4; chr19:55158661-55166722 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human DNAAF3

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Chemically induced (ENU)(1) Gene trapped(2) Targeted(2)
Incidental mutations (data from CvDC )
Human Diseases Modeled in Mice Using Dnaaf3 (1)    Mutations Annotated to Human Diseases (1)    Phenotype Images(17)
Interactions
Dnaaf3 interacts with 60 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process axonemal dynein complex assembly, cell projection organization, ...
Component cytoplasm
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(6)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dnaaf3    NEW 
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000027090 (Evidence)
Ensembl Gene Model ENSMUSG00000055809 (Evidence)
Entrez Gene 436022 (Evidence)
UniGene 425359
DFCI TC1587494
DoTS DT.94385569
NIA Mouse Gene Index U211647
Consensus CDS Project CCDS20737.1
International Mouse Phenotyping Consortium Status Dnaaf3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027090 VEGA Gene Model | MGI Sequence Detail 9521 C57BL/6J ±  kb
transcript OTTMUST00000066991 VEGA | MGI Sequence Detail 2224 Not Applicable 
polypeptide OTTMUSP00000033647 VEGA | MGI Sequence Detail 586 Not Applicable 

For the selected sequences
All sequences(18) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(59 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000031878 dynein assembly factor 3, axonemal
References
(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:222159 Li Y, et al., Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Nature. 2015 May 28;521(7553):520-4
All references(28)
Disease annotation references (1)
Other
accession IDs
MGI:5442114

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory