Dnaaf3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnaaf3
dynein, axonemal assembly factor 3
MGI:3588207

34 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnaaf3^b2b1739Clo/Dnaaf3^b2b1739Clo C57BL/6J-Dnaaf3^b2b1739Clo	abdominal situs ambiguus	J:175213
	abdominal situs inversus	J:175213
	abnormal aortic arch morphology	J:175213
	abnormal inferior vena cava morphology	J:175213
	abnormal liver morphology	J:175213
	abnormal vein morphology	J:175213
	abnormal vertebral column morphology	J:175213
	dextrocardia	J:175213
	dual inferior vena cava	J:175213
	heterotaxia	J:175213
	immotile respiratory cilia	J:175213
	left pulmonary isomerism	J:175213
	right aortic arch	J:175213
	situs inversus totalis	J:175213
Dnaaf3^em1(IMPC)J/Dnaaf3^em1(IMPC)J C57BL/6NJ-Dnaaf3^em1(IMPC)J/Mmjax	abnormal body wall morphology	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Dnaaf3^em1Yoga/Dnaaf3^em1Yoga involves: 129 * C57BL/6J	lethality during fetal growth through weaning, complete penetrance	J:354218
Dnaaf3^em1Yoga/Dnaaf3^em1Yoga involves: 129 * C57BL/6J	postnatal lethality, complete penetrance	J:354218
Dnaaf3^em1Yoga/Dnaaf3^em1Yoga involves: C57BL/6J	abnormal pulmonary alveolus epithelial cell morphology	J:354218
	abnormal pulmonary vein morphology	J:354218
	abnormal spermatocyte morphology	J:354218
	abnormal spermiogenesis	J:354218
	absent acrosome	J:354218
	decreased body weight	J:354218
	decreased spermatid number	J:354218
	dilated brain ventricle	J:354218
	increased brain size	J:354218
	megacephaly	J:354218
	normal mortality/aging	J:354218
	non-obstructive hydrocephaly	J:354218
	postnatal lethality, complete penetrance	J:354218
	small seminiferous tubules	J:354218
	testis hypoplasia	J:354218
	thick pulmonary interalveolar septum	J:354218
	thin cerebral cortex	J:354218

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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