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Evi2 Gene Detail
Summary
  • Symbol
    Evi2
  • Name
    ecotropic viral integration site 2
  • Synonyms
    Gm21975
  • Feature Type
    protein coding gene
  • IDs
    MGI:5439444
    NCBI Gene: 101488212
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:79404211-79421385 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5439444
protein coding gene Chr11:79404211-79421435 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018798
protein coding gene Chr11:80621788-80639002 (-)
A/J MGP_AJ_G0018765
protein coding gene Chr11:77518767-77535973 (-)
AKR/J MGP_AKRJ_G0018735
protein coding gene Chr11:79845883-79863082 (-)
BALB/cJ MGP_BALBcJ_G0018738
protein coding gene Chr11:77927256-77944586 (-)
C3H/HeJ MGP_C3HHeJ_G0018552
protein coding gene Chr11:79903816-79921700 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019190
protein coding gene Chr11:83099269-83116401 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016824
protein coding gene Chr11:74465322-74483693 (-)
CAST/EiJ MGP_CASTEiJ_G0018107
protein coding gene Chr11:80372486-80391203 (-)
CBA/J MGP_CBAJ_G0018523
protein coding gene Chr11:86717777-86735172 (-)
DBA/2J MGP_DBA2J_G0018631
protein coding gene Chr11:77069907-77087142 (-)
FVB/NJ MGP_FVBNJ_G0018620
protein coding gene Chr11:76667739-76684917 (-)
LP/J MGP_LPJ_G0018701
protein coding gene Chr11:81130402-81150748 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018647
protein coding gene Chr11:87015308-87034789 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019230
protein coding gene Chr11:80106975-80124161 (-)
PWK/PhJ MGP_PWKPhJ_G0017877
protein coding gene Chr11:77886297-77903465 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017668
protein coding gene Chr11:79711103-79729584 (-)
WSB/EiJ MGP_WSBEiJ_G0018159
protein coding gene Chr11:79931522-79948731 (-)



Homology
more
  • Human Ortholog
    EVI2B, ecotropic viral integration site 2B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EVI2B, ecotropic viral integration site 2B
  • Synonyms
    CD361, D17S376, EVDB
  • Links
    NCBI Gene ID: 2124
    neXtProt AC: NX_P34910
    UniProt: P34910

  • Chr Location
    17q11.2; chr17:31303770-31314105 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070354 Ensembl Gene Model | MGI Sequence Detail 17175 C57BL/6J ±  kb
transcript ENSMUST00000093983 Ensembl | MGI Sequence Detail 3914 Not Applicable  
polypeptide ENSMUSP00000091519 Ensembl | MGI Sequence Detail 77 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 15
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory