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Xaf1
Gene Detail
 Symbol
Name
ID
Xaf1
XIAP associated factor 1
MGI:3772572
Feature Type protein coding gene
Genetic Map
Chromosome 11
43.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:72301629-72313733 bp, + strand
From VEGA annotation of GRCm38

  12105 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49488  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 chicken; 1 zebrafish

Gene Tree: Xaf1

Human
homologs
Human Homolog XAF1, XIAP associated factor 1
NCBI Gene ID 54739
neXtProt AC  NX_Q6GPH4
Human Synonyms  BIRC4BP, HSXIAPAF1, XIAPAF1
Human Chr (Location)  17p13.1; chr17:6755837-6775647 (+)  GRCh38
Alleles
and
phenotypes
All alleles(1) : Gene trapped(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process apoptotic process, negative regulation of protein complex assembly, ...
Component cytoplasm, mitochondrion, ...
Function metal ion binding
Expression
cDNA source data(14)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(14) cDNA(14)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000006106 (Evidence)
Ensembl Gene ModelENSMUSG00000040483 (Evidence)
Entrez Gene327959 (Evidence)
UniGene291131
DFCITC1587522, TC1624897, TC1667977, TC1676840, TC1687442
DoTSDT.101237489, DT.40134578, DT.40138320, DT.55272698, DT.91322501
NIA Mouse Gene IndexU012878
Consensus CDS ProjectCCDS24984.2, CCDS70236.1
International Mouse Knockout Project StatusXaf1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006106 VEGA Gene Model | MGI Sequence Detail 12105 C57BL/6J ±  kb
transcript OTTMUST00000013799 VEGA | MGI Sequence Detail 2597 Not Applicable 
polypeptide OTTMUSP00000006397 VEGA | MGI Sequence Detail 273 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(16) UniProt(3)
Polymorphisms SNPs within 2kb(126 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
Protein Ontology PR:000017471 XIAP-associated factor 1
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:91241 Wang X, et al., X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia. Neurobiol Dis. 2004 Jun;16(1):179-89
All references(25)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory