About   Help   FAQ
Mir449b Gene Detail
Summary
  • Symbol
    Mir449b
  • Name
    microRNA 449b
  • Synonyms
    Mirn449b, mmu-mir-449b
Location &
Maps
more
  • Sequence Map
    Chr13:113173953-113174032 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 63.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3718803
miRNA gene Chr13:113173953-113174032 (+)
129S1/SvImJ ENSMUSG00200031840
miRNA gene Chr13:107638161-107638240 (+)
A/J ENSMUSG00195013478
miRNA gene Chr13:108147178-108147262 (+)
AKR/J ENSMUSG00220032595
miRNA gene Chr13:106584594-106584673 (+)
BALB/cJ ENSMUSG00180031630
miRNA gene Chr13:108734630-108734709 (+)
C3H/HeJ ENSMUSG00175028327
miRNA gene Chr13:108812208-108812287 (+)
C57BL/6NJ ENSMUSG00215026059
miRNA gene Chr13:108834251-108834330 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007353
miRNA gene Chr13:106308357-106308438 (+)
CAST/EiJ ENSTCUG00005025777
miRNA gene Chr13:107860794-107860875 (+)
CBA/J ENSMUSG00210011000
miRNA gene Chr13:108149853-108149932 (+)
DBA/2J ENSMUSG00185029953
miRNA gene Chr13:111908454-111908533 (+)
FVB/NJ ENSMUSG00205007146
miRNA gene Chr13:107592915-107592999 (+)
JF1/MsJ ENSUMUG00000014409
miRNA gene Chr13:111374632-111374716 (+)
LP/J ENSMUSG00230012227
miRNA gene Chr13:122107100-122107179 (+)
NOD/ShiLtJ ENSMUSG00190019335
miRNA gene Chr13:108432960-108433039 (+)
NZO/HlLtJ ENSMUSG00225031241
miRNA gene Chr13:114294618-114294702 (+)
PWK/PhJ ENSLUMG00010010434
miRNA gene Chr13:107405213-107405297 (+)
SPRET/EiJ ENSMSPG00010017583
miRNA gene Chr13:109120628-109120709 (+)
WSB/EiJ ENSIUOG00005010036
miRNA gene Chr13:107604892-107604971 (+)



Homology
more
  • Human Ortholog
    MIR449B, microRNA 449b
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR449B, microRNA 449b
  • Synonyms
    mir-449b, MIRN449B
  • Links
    NCBI Gene ID: 693123

  • Chr Location
    chr5:55170646-55170742 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 100190765 NCBI Gene Model | MGI Sequence Detail 80 C57BL/6J ±  kb
transcript NR_030602 RefSeq | MGI Sequence Detail 80 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    Primer pair 2
    Other 1
Other Database
Links
less
miRBase MI0005547
References
more
  • Summaries
    All 20
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:349837 Liu H, et al., A local translation program regulates centriole amplification in the airway epithelium. Sci Rep. 2023 May 1;13(1):7090

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/08/2026
MGI 6.24
The Jackson Laboratory