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H3f4 Gene Detail
Summary
  • Symbol
    H3f4
  • Name
    H3.4 histone
  • Synonyms
    Gm12260, H304, H3mmT, H3t
Location &
Maps
more
  • Sequence Map
    Chr11:58961812-58962222 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 36.39 cM
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651326
protein coding gene Chr11:58961711-58962273 (+)
129S1/SvImJ MGP_129S1SvImJ_G0039971
pseudogene Chr11:58743629-58744039 (+)
A/J MGP_AJ_G0039978
pseudogene Chr11:56503244-56503654 (+)
AKR/J MGP_AKRJ_G0039898
pseudogene Chr11:58403704-58404114 (+)
BALB/cJ MGP_BALBcJ_G0039956
pseudogene Chr11:56870194-56870604 (+)
C3H/HeJ MGP_C3HHeJ_G0039603
pseudogene Chr11:58291067-58291477 (+)
C57BL/6NJ MGP_C57BL6NJ_G0040535
pseudogene Chr11:60619625-60620035 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0037092
pseudogene Chr11:53775781-53776191 (+)
CAST/EiJ MGP_CASTEiJ_G0038711
pseudogene Chr11:58408520-58408930 (+)
CBA/J MGP_CBAJ_G0039572
pseudogene Chr11:63264511-63264921 (+)
DBA/2J MGP_DBA2J_G0039769
pseudogene Chr11:56181020-56181430 (+)
FVB/NJ MGP_FVBNJ_G0039733
pseudogene Chr11:55828948-55829358 (+)
LP/J MGP_LPJ_G0039805
pseudogene Chr11:59359315-59359725 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0039718
pseudogene Chr11:64419248-64419658 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0040626
pseudogene Chr11:58408516-58408926 (+)
PWK/PhJ MGP_PWKPhJ_G0038389
pseudogene Chr11:56766220-56766630 (+)
SPRET/EiJ MGP_SPRETEiJ_G0038120
pseudogene Chr11:58216503-58216913 (+)
WSB/EiJ MGP_WSBEiJ_G0038933
pseudogene Chr11:58093701-58094111 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Genomic Mutations
    1 involving H3f4
  • Find Mice (IMSR)
Mice homozygous for a knock-out allele exhibit male infertility associated with small testes, meiotic failure, increased male germ cell apoptosis, and azoospermia.
Expression
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000080152 Ensembl Gene Model | MGI Sequence Detail 411 C57BL/6J ±  kb
transcript ENSMUST00000122447 Ensembl | MGI Sequence Detail 411 Not Applicable  
polypeptide NP_001304932 RefSeq | MGI Sequence Detail 136 C57BL/6  
For the selected sequence
References
more
  • Summaries
    All 12
    Phenotypes 4
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:258191 Ueda J, et al., Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis. Cell Rep. 2017 Jan 17;18(3):593-600

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory