H3f4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H3f4
H3.4 histone, cluster member
MGI:3651326

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
H3f4^em1Aha/H3f4^em1Aha Not Specified	abnormal cauda epididymis morphology	J:360728
	abnormal double-strand DNA break repair	J:360728
	abnormal hormone level	J:360728
	abnormal peritubular myoid cell morphology	J:360728
	abnormal progesterone level	J:360728
	abnormal seminiferous tubule morphology	J:360728
	abnormal spermatogenesis	J:360728
	abnormal testis interstitial tissue morphology	J:360728
	abnormal testosterone level	J:360728
	azoospermia	J:360728
	decreased male germ cell number	J:360728
	early cellular replicative senescence	J:360728
	increased Leydig cell number	J:360728
	increased Sertoli cell number	J:360728
	increased testes secretion	J:360728
	oxidative stress	J:360728
	small seminiferous tubules	J:360728
	small testis	J:360728
	testicular atrophy	J:360728
H3f4^em1Osb/H3f4^em1Osb involves: C57BL/6	abnormal cauda epididymis morphology	J:258191
	abnormal male meiosis	J:258191
	abnormal spermatocyte morphology	J:258191
	abnormal spermatogenesis	J:258191
	abnormal spermatogonia morphology	J:258191
	azoospermia	J:258191
	decreased elongated spermatid number	J:258191
	decreased male germ cell number	J:258191
	increased male germ cell apoptosis	J:258191
	male infertility	J:258191
	normal reproductive system phenotype	J:258191
	small testis	J:258191

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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