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Ifna15 Gene Detail
Summary
  • Symbol
    Ifna15
  • Name
    interferon alpha 15
  • Synonyms
    Gm12597, Ifnaa
  • Feature Type
    protein coding gene
  • IDs
    MGI:3649418
    NCBI Gene: 242517
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr4:88475910-88476482 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 41.96 cM
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3649418
protein coding gene Chr4:88475910-88476482 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028422
protein coding gene Chr4:88435642-88436214 (-)
A/J MGP_AJ_G0028383
protein coding gene Chr4:85345873-85348068 (-)
AKR/J MGP_AKRJ_G0028332
protein coding gene Chr4:87459521-87460093 (-)
BALB/cJ MGP_BALBcJ_G0028403
protein coding gene Chr4:85559464-85560036 (-)
C3H/HeJ MGP_C3HHeJ_G0028118
protein coding gene Chr4:88177955-88178527 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028842
protein coding gene Chr4:91805758-91806330 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026142
protein coding gene Chr4:81331932-81332874 (-)
CAST/EiJ MGP_CASTEiJ_G0027559
protein coding gene Chr4:86016202-86103792 (-)
CBA/J MGP_CBAJ_G0028087
protein coding gene Chr4:94637977-94638549 (-)
DBA/2J MGP_DBA2J_G0028236
protein coding gene Chr4:85105679-85106251 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0028336
protein coding gene Chr4:88787669-88788241 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028231
protein coding gene Chr4:99628737-99629309 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028879
protein coding gene Chr4:87593735-87594307 (-)
PWK/PhJ MGP_PWKPhJ_G0027282
protein coding gene Chr4:83426128-83513023 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027107
protein coding gene Chr4:85100274-85203741 (-)
WSB/EiJ MGP_WSBEiJ_G0027635
protein coding gene Chr4:87799301-87799829 (-)



Homology
more
  • Human Ortholog
    IFNA1, interferon alpha 1
  • Vertebrate Orthologs
    16
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFNA1, interferon alpha 1
  • Synonyms
    IFL, IFN, IFNA@, IFNA13, IFN-ALPHA, IFN-alphaD, leIF D
  • Links
    NCBI Gene ID: 3439
    neXtProt AC: NX_P01562
    UniProt: P01562

  • Chr Location
    9p21.3; chr9:21440439-21441316 (+)  GRCh38

  • Human Ortholog
    IFNA10, interferon alpha 10
  • Synonyms
    IFN-alphaC
  • Links
    NCBI Gene ID: 3446
    neXtProt AC: NX_P01566
    UniProt: P01566

  • Chr Location
    9p21.3; chr9:21206181-21207143 (-)  GRCh38

  • Human Ortholog
    IFNA13, interferon alpha 13
  • Links
    NCBI Gene ID: 3447
    neXtProt AC: NX_P01562
    UniProt: P01562

  • Chr Location
    9p21.3; chr9:21367372-21368057 (-)  GRCh38

  • Human Ortholog
    IFNA14, interferon alpha 14
  • Synonyms
    IFN-alphaH, LEIF2H
  • Links
    NCBI Gene ID: 3448
    neXtProt AC: NX_P01570
    UniProt: P01570

  • Chr Location
    9p21.3; chr9:21239002-21240005 (-)  GRCh38

  • Human Ortholog
    IFNA16, interferon alpha 16
  • Synonyms
    IFN-alpha-16, IFN-alphaO
  • Links
    NCBI Gene ID: 3449
    neXtProt AC: NX_P05015
    UniProt: P05015

  • Chr Location
    9p21.3; chr9:21216373-21217311 (-)  GRCh38

  • Human Ortholog
    IFNA17, interferon alpha 17
  • Synonyms
    IFNA, IFN-alphaI, INFA, LEIF2C1
  • Links
    NCBI Gene ID: 3451
    neXtProt AC: NX_P01571
    UniProt: P01571

  • Chr Location
    9p21.3; chr9:21227243-21228222 (-)  GRCh38

  • Human Ortholog
    IFNA2, interferon alpha 2
  • Synonyms
    IFNA, IFNA2B, IFN-alpha-2, IFN-alphaA, leIF A
  • Links
    NCBI Gene ID: 3440
    neXtProt AC: NX_P01563
    UniProt: P01563

  • Chr Location
    9p21.3; chr9:21384255-21385398 (-)  GRCh38

  • Human Ortholog
    IFNA21, interferon alpha 21
  • Synonyms
    IFN-alphaI, leIF-F, LeIF F
  • Links
    NCBI Gene ID: 3452
    neXtProt AC: NX_P01568
    UniProt: P01568

  • Chr Location
    9p21.3; chr9:21165637-21166660 (-)  GRCh38

  • Human Ortholog
    IFNA4, interferon alpha 4
  • Synonyms
    IFN-alpha4a, INFA4
  • Links
    NCBI Gene ID: 3441
    neXtProt AC: NX_P05014
    UniProt: P05014

  • Chr Location
    9p21.3; chr9:21186618-21187587 (-)  GRCh38

  • Human Ortholog
    IFNA5, interferon alpha 5
  • Synonyms
    IFN-alpha-5, IFN-alphaG, INA5, INFA5, leIF G
  • Links
    NCBI Gene ID: 3442
    neXtProt AC: NX_P01569
    UniProt: P01569

  • Chr Location
    9p21.3; chr9:21304326-21305313 (-)  GRCh38

  • Human Ortholog
    IFNA6, interferon alpha 6
  • Synonyms
    IFN-alphaK
  • Links
    NCBI Gene ID: 3443
    neXtProt AC: NX_P05013
    UniProt: P05013

  • Chr Location
    9p21.3; chr9:21350253-21350956 (-)  GRCh38

  • Human Ortholog
    IFNA7, interferon alpha 7
  • Synonyms
    IFNA-J, IFN-alphaJ
  • Links
    NCBI Gene ID: 3444
    neXtProt AC: NX_P01567
    UniProt: P01567

  • Chr Location
    9p21.3; chr9:21201469-21202205 (-)  GRCh38

  • Human Ortholog
    IFNA8, interferon alpha 8
  • Synonyms
    IFN-alphaB
  • Links
    NCBI Gene ID: 3445
    neXtProt AC: NX_P32881
    UniProt: P32881

  • Chr Location
    9p21.3; chr9:21409117-21410185 (+)  GRCh38

Human Diseases
more
  • Diseases
    6 with human IFNA1,IFNA17,IFNA2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    3
  • Radiation induced
    1
  • Genomic Mutations
    5 involving Ifna15
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 242517 NCBI Gene Model | MGI Sequence Detail 573 C57BL/6J ±  kb
transcript NM_206870 RefSeq | MGI Sequence Detail 573 Not Specified  
polypeptide NP_996753 RefSeq | MGI Sequence Detail 190 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR009079 Four-helical cytokine-like, core
    IPR000471 Interferon alpha/beta/delta
Molecular
Reagents
less
  • All nucleic 2
    Genomic 1
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:17550 Daugherty B, et al., Isolation and bacterial expression of a murine alpha leukocyte interferon gene. J Interferon Res. 1984 Fall;4(4):635-43
  • Latest
    J:235276 Saito M, et al., Identification of Stmm3 locus conferring resistance to late-stage chemically induced skin papillomas on mouse chromosome 4 by congenic mapping and allele-specific alteration analysis. Exp Anim. 2014;63(3):339-48

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory