Phf11 Pseudogene Detail

Summary

• Symbol
  Phf11
• Name
  PHD finger protein 11
• Synonyms
  Gm6904, Phf11-ps

• Feature Type
  pseudogene
• IDs
  MGI:3644962
  NCBI Gene: 628693
• Alliance
  genome feature page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr14:59482149-59497629 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 31.48 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  582 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3644962	pseudogene	Chr14:59476216-59497638 (-)
129S1/SvImJ	ENSMUSG00200045087	pseudogene	Chr14:48068037-48083518 (-)
A/J	ENSMUSG00195035606	pseudogene	Chr14:48285443-48300925 (-)
AKR/J	ENSMUSG00220036243	pseudogene	Chr14:47623467-47638937 (-)
BALB/cJ	ENSMUSG00180053301	pseudogene	Chr14:47907436-47922917 (-)
C3H/HeJ	ENSMUSG00175052016	pseudogene	Chr14:49620791-49641656 (-)
C57BL/6NJ	ENSMUSG00215049922	pseudogene	Chr14:47806085-47821566 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	ENSTCUG00005050461	pseudogene	Chr14:49628989-49639072 (-)
CBA/J	ENSMUSG00210048969	pseudogene	Chr14:48275667-48291148 (-)
DBA/2J	ENSMUSG00185033965	pseudogene	Chr14:53419006-53439871 (-)
FVB/NJ	ENSMUSG00205046260	pseudogene	Chr14:47681993-47697476 (-)
JF1/MsJ	ENSUMUG00000049239	pseudogene	Chr14:64589950-64644576 (-)
LP/J	ENSMUSG00230037265	pseudogene	Chr14:65437005-65452488 (-)
NOD/ShiLtJ	ENSMUSG00190049969	pseudogene	Chr14:48039970-48055451 (-)
NZO/HlLtJ	ENSMUSG00225047434	pseudogene	Chr14:55737496-55752980 (-)
PWK/PhJ	ENSLUMG00010052024	pseudogene	Chr14:47492729-47508210 (-)
SPRET/EiJ	ENSMSPG00010035292	pseudogene	Chr14:51024794-51041814 (-)
WSB/EiJ	ENSIUOG00005046406	pseudogene	Chr14:47471921-47487417 (-)

Homology

• Human Ortholog
  PHF11, PHD finger protein 11

• Vertebrate Orthologs
  1

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  PHF11, PHD finger protein 11
  
• Synonyms
  APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34
• Links
  HGNC:17024

  NCBI Gene ID: 51131

  UniProt: Q9UIL8

  
  
• Chr Location
  13q14.2; chr13:49495095-49528981 (+)  GRCh38

---

• MGI Vertebrate Homology
  Phf11 stringent orthology
  1 human;1 mouse
  
• HCOP
  vertebrate homology predictions: PHF11
• Gene Tree
  Phf11
  

Human Diseases

• Diseases
  4 with human PHF11 associations

				Human Disease	Mouse Models
				allergic disease IDs allergic disease       DOID:1205 ICD10CM:T78.40 MESH:D006967 NCI:C3114 UMLS_CUI:C0020517
				asthma IDs asthma       DOID:2841 DOID:12703 DOID:13829 DOID:13830 DOID:2840 DOID:5783 ICD10CM:J45 ICD9CM:493 ICD9CM:493.9 KEGG:05310 MESH:D001249 NCI:C28397 OMIM:600807 UMLS_CUI:C0004096
				atopic dermatitis IDs atopic dermatitis       DOID:3310 EFO:0000274 ICD10CM:L20 MESH:D003876 NCI:C211594 OMIM:603165 OMIM:PS603165 UMLS_CUI:C0011615
				childhood-onset asthma IDs childhood-onset asthma       DOID:0080815

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Targeted
  1
• Genomic Mutations
  1 involving Phf11
• Find Mice (IMSR)
  13 strains or lines available

Expression

• Assay Results
  597

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  22
• RefSeq
  1
• CCDS
  CCDS49509.1

• Ensembl
  ENSMUSG00000090881 (Evidence)
• NCBI Gene
  628693

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000090881	Ensembl Gene Model | MGI Sequence Detail	15481	C57BL/6J
transcript	ENSMUST00000224042	Ensembl | MGI Sequence Detail	603	Not Applicable

Other
Accession IDs

MGI:6286506, MGI:6355963

References

• Summaries
  All 11

  Phenotypes 3
• Earliest
  J:217094 Zhang Y, et al., Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant. Mamm Genome. 2014 Dec;25(11-12):573-82
• Latest
  J:238694 Gong Y, et al., PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017 Jan 01;31(1):46-58

TSS for Phf11:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr128993	Chr14:59497634-59497640 (-)	-8 bp