Zbtb42 Gene Detail

Summary

• Symbol
  Zbtb42
• Name
  zinc finger and BTB domain containing 42
• Synonyms
  Gm5188, simiRP58

• Feature Type
  protein coding gene
• IDs
  MGI:3644133
  NCBI Gene: 382639
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr12:112678828-112682747 bp, + strand
• From Ensembl annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, 61.20 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  75 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3644133	protein coding gene	Chr12:112678648-112682747 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020157	protein coding gene	Chr12:115147713-115151084 (+)
A/J	MGP_AJ_G0020113	protein coding gene	Chr12:110708734-110712691 (+)
AKR/J	MGP_AKRJ_G0020088	protein coding gene	Chr12:113897877-113901832 (+)
BALB/cJ	MGP_BALBcJ_G0020098	protein coding gene	Chr12:111153059-111156980 (+)
C3H/HeJ	MGP_C3HHeJ_G0019900	protein coding gene	Chr12:114407417-114411372 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020543	protein coding gene	Chr12:118706066-118711910 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018157	protein coding gene	Chr12:107139411-107143378 (+)
CAST/EiJ	MGP_CASTEiJ_G0019440	protein coding gene	Chr12:109255005-109258962 (+)
CBA/J	MGP_CBAJ_G0019867	protein coding gene	Chr12:123242094-123246049 (+)
DBA/2J	MGP_DBA2J_G0019984	protein coding gene	Chr12:110187617-110191553 (+)
FVB/NJ	MGP_FVBNJ_G0019969	protein coding gene	Chr12:109013707-109017663 (+)
LP/J	MGP_LPJ_G0020058	protein coding gene	Chr12:114975058-114980123 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020007	protein coding gene	Chr12:126327382-126332709 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020572	protein coding gene	Chr12:113422750-113429551 (+)
PWK/PhJ	MGP_PWKPhJ_G0019202	protein coding gene	Chr12:104845911-104849982 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019006	protein coding gene	Chr12:107585325-107589247 (+)
WSB/EiJ	MGP_WSBEiJ_G0019500	protein coding gene	Chr12:114329702-114333660 (+)

Homology

• Human Ortholog
  ZBTB42, zinc finger and BTB domain containing 42

• Vertebrate Orthologs
  6

• Human Ortholog
  ZBTB42, zinc finger and BTB domain containing 42
  Orthology source: HomoloGene, HGNC
• Synonyms
  LCCS6, ZNF925
• Links
  HGNC:32550

  NCBI Gene ID: 100128927

  neXtProt AC: NX_B2RXF5

  UniProt: B2RXF5

  
  
• Chr Location
  14q32.33; chr14:104800597-104804712 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 20003
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 macaque, rhesus
  
• HCOP
  human homology predictions: ZBTB42
• Gene Tree
  Zbtb42
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  8 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  13
• GO References
  6

Expression

• cDNA Data
  22

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Zbtb42 interacts with 283 markers (Mir1b, Mir7-1, Mir7-2, ...) View All

Sequences &
Gene Models

• All Sequences
  41
• RefSeq
  4
• UniProt
  3
• CCDS
  CCDS49190.1
• UniGene
  11350

• Ensembl
  ENSMUSG00000037638 (Evidence)
• NCBI Gene
  382639

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000037638	Ensembl Gene Model | MGI Sequence Detail	3920	C57BL/6J
transcript	ENSMUST00000169593	Ensembl | MGI Sequence Detail	3478	Not Applicable
polypeptide	ENSMUSP00000133152	Ensembl | MGI Sequence Detail	420	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000017583 zinc finger and BTB domain-containing protein 42
  (term hierarchy)
• InterPro Domains
  IPR000210 BTB/POZ domain
  IPR011333 SKP1/BTB/POZ domain superfamily
  IPR036236 Zinc finger C2H2 superfamily
  IPR013087 Zinc finger C2H2-type

Molecular
Reagents

• All nucleic 22

  cDNA 22

  
  

  Microarray probesets 1

References

• Summaries
  All 20

  Gene Ontology 6

  Phenotypes 1
• Earliest
  J:91257 Gray PA, et al., Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
• Latest
  J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

TSS for Zbtb42:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr115392	Chr12:112678782-112678798 (+)	-38 bp
Tssr115393	Chr12:112678803-112678823 (+)	-15 bp