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Cyp2c54 Gene Detail
Summary
  • Symbol
    Cyp2c54
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 54
  • Feature Type
    protein coding gene
  • IDs
    MGI:3642960
    NCBI Gene: 404195
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:40026384-40062271 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 34.24 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    133 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642960
 protein coding gene Chr19:40026383-40062289 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025107
 protein coding gene Chr19:39218755-39262877 (-)
A/J MGP_AJ_G0025084
 protein coding gene Chr19:37298591-37344535 (-)
AKR/J MGP_AKRJ_G0025052
 protein coding gene Chr19:38576494-38611328 (-)
BALB/cJ MGP_BALBcJ_G0025078
 protein coding gene Chr19:37384812-37423456 (-)
C3H/HeJ MGP_C3HHeJ_G0024838
 protein coding gene Chr19:38682937-38722461 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025523
 protein coding gene Chr19:40265089-40313971 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022935
 protein coding gene Chr19:36808584-36817361 (+)
CAST/EiJ MGP_CASTEiJ_G0024303
 protein coding gene Chr19:38347736-38378340 (-)
CBA/J MGP_CBAJ_G0024818
 protein coding gene Chr19:42251799-42291833 (-)
DBA/2J MGP_DBA2J_G0024950
 protein coding gene Chr19:37193480-37233174 (-)
FVB/NJ MGP_FVBNJ_G0024911
 protein coding gene Chr19:36958298-36999502 (-)
LP/J MGP_LPJ_G0025036
 protein coding gene Chr19:39246439-39279818 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024942
 protein coding gene Chr19:41921812-41970502 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025579
 protein coding gene Chr19:38613007-38649004 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0023856
 protein coding gene Chr19:37335341-37383441 (-)
WSB/EiJ MGP_WSBEiJ_G0024373
 protein coding gene Chr19:38757449-38790982 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    29
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067225 Ensembl Gene Model | MGI Sequence Detail 35888 C57BL/6J ±  kb
transcript ENSMUST00000048959 Ensembl | MGI Sequence Detail 1786 Not Applicable  
polypeptide ENSMUSP00000048284 Ensembl | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:113341 Wang H, et al., Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities. Mol Pharmacol. 2004 May;65(5):1148-58
  • Latest
    J:341617 Zhang J, et al., CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 Jul;37(7):e23009
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory