Cyp2c54
Gene Detail

Symbol Name ID

Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 MGI:3642960

Feature Type

protein coding gene

Genetic Map

Chromosome 19

34.24 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr19:40037941-40073811 bp, - strand From Ensembl annotation of GRCm38   35871 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:113709  Vertebrate Homology Class
1 human; 3 mouse; 2 rat; 1 rhesus macaque; 3 cattle; 1 dog

Protein SuperFamily: cytochrome P450 CYP2D6
Gene Tree: Cyp2c54

Human homologs

Human Homolog		CYP2C18, cytochrome P450, family 2, subfamily C, polypeptide 18
NCBI Gene ID		1562
neXtProt AC		NX_P33260
Human Synonyms		CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
Human Chr (Location)		10q24; chr10:96443251-96495947 (+)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	oxidation-reduction process
Component	endoplasmic reticulum, intracellular membrane-bounded organelle, ...
Function	aromatase activity, electron carrier activity, ...

Expression

cDNA source data(29)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(30) cDNA(29) Other(1)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000067225 (Evidence)
Entrez Gene	404195 (Evidence)
UniGene	379575
NIA Mouse Gene Index	U090833
EC	1.14.14.1
Consensus CDS Project	CCDS29800.1
International Mouse Knockout Project Status	Cyp2c54

Sequences

Length	Strain/Species
genomic	ENSMUSG00000067225	Ensembl Gene Model | MGI Sequence Detail	35871	C57BL/6J
transcript	ENSMUST00000048959	Ensembl | MGI Sequence Detail	1769	Not Applicable
polypeptide	ENSMUSP00000048284	Ensembl | MGI Sequence Detail	490	Not Applicable

All sequences(15) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(44 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001128	Cytochrome P450
InterPro	IPR017972	Cytochrome P450, conserved site
InterPro	IPR002401	Cytochrome P450, E-class, group I
Protein Ontology	PR:000006231	cytochrome P450 2C54

References

(Earliest) J:113341 Wang H, et al., Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities. Mol Pharmacol. 2004 May;65(5):1148-58
(Latest) J:141632 Kasai F, et al., Emergence of complex rearrangements at translocation breakpoints in a transgenic mouse; implications for mechanisms involved in the formation of chromosome rearrangements. Cytogenet Genome Res. 2007;119(1-2):83-90
All references(15)