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Mir449c Gene Detail
Summary
  • Symbol
    Mir449c
  • Name
    microRNA 449c
  • Synonyms
    microRNA 449c, Mirn449c, mmu-mir-449c
Location &
Maps
more
  • Sequence Map
    Chr13:113172517-113172625 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 63.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    29 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3639505
miRNA gene Chr13:113172517-113172625 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008098
miRNA gene Chr13:115643109-115643217 (+)
A/J MGP_AJ_G0008086
miRNA gene Chr13:111016625-111016733 (+)
AKR/J MGP_AKRJ_G0008066
miRNA gene Chr13:114366701-114366809 (+)
BALB/cJ MGP_BALBcJ_G0008068
miRNA gene Chr13:111712202-111712310 (+)
C3H/HeJ MGP_C3HHeJ_G0008012
miRNA gene Chr13:114157064-114157172 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008255
miRNA gene Chr13:119064456-119064564 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007352
miRNA gene Chr13:106306904-106307012 (+)
CAST/EiJ MGP_CASTEiJ_G0007892
miRNA gene Chr13:113798616-113798724 (+)
CBA/J MGP_CBAJ_G0007980
miRNA gene Chr13:123670940-123671048 (+)
DBA/2J MGP_DBA2J_G0008015
miRNA gene Chr13:110728065-110728173 (+)
FVB/NJ MGP_FVBNJ_G0008039
miRNA gene Chr13:109428679-109428787 (+)
LP/J MGP_LPJ_G0008098
miRNA gene Chr13:115676755-115676863 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008007
miRNA gene Chr13:123925166-123925274 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008253
miRNA gene Chr13:113832260-113832368 (+)
PWK/PhJ MGP_PWKPhJ_G0007812
miRNA gene Chr13:109478267-109478375 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007709
miRNA gene Chr13:110146335-110146443 (+)
WSB/EiJ MGP_WSBEiJ_G0007966
miRNA gene Chr13:114428880-114428988 (+)



Homology
more
  • Human Ortholog
    MIR449C, microRNA 449c
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR449C, microRNA 449c
  • Synonyms
    mir-449c
  • Links
    NCBI Gene ID: 100313923

  • Chr Location
    chr5:55172262-55172353 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
Representative SequencesLengthStrain/SpeciesFlank
genomic 735309 NCBI Gene Model | MGI Sequence Detail 109 C57BL/6J ±  kb
transcript NR_030452 RefSeq | MGI Sequence Detail 109 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 4
    Primer pair 1
    Other 3
Other Database
Links
less
miRBase MI0004645
References
more
  • Summaries
    All 18
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:341749 Chen TH, et al., MiR34 contributes to spinal muscular atrophy and AAV9-mediated delivery of MiR34a ameliorates the motor deficits in SMA mice. Mol Ther Nucleic Acids. 2023 Jun 13;32:144-160

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory