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Adamts17
Gene Detail
Symbol

Name
ID
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
MGI:3588195
Synonyms
AU023434
Feature Type
protein coding gene
Genetic Map
Chromosome 7
36.26 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:66839735-67152625 bp, + strand
From VEGA annotation of GRCm38

  312891 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16373  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ADAMTS17
Gene Tree: Adamts17

Human
homologs
ADAMTS17, ADAM metallopeptidase with thrombospondin type 1 motif, 17
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 170691
neXtProt AC: NX_Q8TE56

Human Chr (Location): 15q24; chr15:99971438-100342087 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human ADAMTS17

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Adamts17 interacts with 320 markers (Mir1b, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (2)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 1
RT-PCR 1
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase adamts17    NEW 
Molecular
reagents
All nucleic(20) cDNA(19) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000024145 (Evidence)
Ensembl Gene Model ENSMUSG00000058145 (Evidence)
Entrez Gene 233332 (Evidence)
UniGene 445763
DFCI TC1591469, TC1620100, TC1656193, TC1713265
DoTS DT.101345521, DT.111005348, DT.521550, DT.91374742, DT.91381846, DT.94280560
NIA Mouse Gene Index U008193
Consensus CDS Project CCDS21349.2
International Mouse Phenotyping Consortium Status Adamts17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024145 VEGA Gene Model | MGI Sequence Detail 312891 C57BL/6J ±  kb
transcript OTTMUST00000059071 VEGA | MGI Sequence Detail 5870 Not Applicable 
polypeptide OTTMUSP00000028701 VEGA | MGI Sequence Detail 1095 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(10) UniProt(6)
Polymorphisms
SNPs within 2kb(3587 from dbSNP Build 137)    SNPs within 2kb including multiple locations(3599)
Protein-related
information
ResourceIDDescription
InterPro IPR010294 ADAM-TS Spacer 1
InterPro IPR024079 Metallopeptidase, catalytic domain
InterPro IPR001590 Peptidase M12B, ADAM/reprolysin
InterPro IPR013273 Peptidase M12B, ADAM-TS
InterPro IPR002870 Peptidase M12B, propeptide
InterPro IPR010909 PLAC
InterPro IPR000884 Thrombospondin, type 1 repeat
InterPro IPR007087 Zinc finger, C2H2
Protein Ontology PR:000030471 a disintegrin and metalloproteinase with thrombospondin motifs 17
References
(Earliest) J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(23)
Other
accession IDs
MGI:3034316

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory