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Symbol Name ID |
Adamts17
ADAM metallopeptidase with thrombospondin type 1 motif 17 MGI:3588195 |
| Age | E7.5 | E13.5 | E14.5 | E16.5 | E17 | P |
| Immunohistochemistry (section) | 2 | 1 | 1 | |||
| In situ RNA (section) | 1 | 1 | 1 | 1 | ||
| RT-PCR | 1 | 3 |
| Adamts17 ADAM metallopeptidase with thrombospondin type 1 motif 17 (Synonyms: AU023434) | |
| Results | Reference |
| 1* | J:165751 Du J, Takeuchi H, Leonhard-Melief C, Shroyer KR, Dlugosz M, Haltiwanger RS, Holdener BC, O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. Dev Biol. 2010 Oct 1;346(1):25-38 |
| 1 | J:324217 Mead TJ, Martin DR, Wang LW, Cain SA, Gulec C, Cahill E, Mauch J, Reinhardt D, Lo C, Baldock C, Apte SS, Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development. Elife. 2022 May 3;11:e71142 |
| 1* | J:158212 Morales J, Al-Sharif L, Khalil DS, Shinwari JM, Bavi P, Al-Mahrouqi RA, Al-Rajhi A, Alkuraya FS, Meyer BF, Al Tassan N, Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. Am J Hum Genet. 2009 Nov;85(5):558-68 |
| 1 | J:324116 Morita R, Sanzen N, Sasaki H, Hayashi T, Umeda M, Yoshimura M, Yamamoto T, Shibata T, Abe T, Kiyonari H, Furuta Y, Nikaido I, Fujiwara H, Tracing the origin of hair follicle stem cells. Nature. 2021 Jun;594(7864):547-552 |
| 1* | J:321553 Neupane S, Berardinelli SJ, Cameron DC, Grady RC, Komatsu DE, Percival CJ, Takeuchi M, Ito A, Liu TW, Nairn AV, Moremen KW, Haltiwanger RS, Holdener BC, O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development. Matrix Biol. 2022 Feb 12; |
| 2 | J:295274 Oichi T, Taniguchi Y, Soma K, Oshima Y, Yano F, Mori Y, Chijimatsu R, Kim-Kaneyama JR, Tanaka S, Saito T, Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway. Cell Mol Life Sci. 2019 Dec;76(23):4795-4809 |
| 5 | J:373026 Taye N, Karoulias SZ, Balic Z, Wang LW, Willard BB, Martin D, Richard D, Okamoto AS, Capellini TD, Apte SS, Hubmacher D, Combined ADAMTS10 and ADAMTS17 inactivation exacerbates bone shortening and skin phenotypes. Life Sci Alliance. 2025 Dec;8(12) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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