hhy
Gene Detail

Symbol Name ID

hhy hemorrhagic hydrocephalus MGI:3505572

Feature Type

heritable phenotypic marker

Genetic Map

Chromosome 12
Syntenic

Mapping data(1)

Alleles and phenotypes

All alleles(1) : Spontaneous(1)
 

Homozygous mutant mice display hydrocephalus, intracranial hemorrhage due to ventricular dilatation, and heterotopia in the subcortical regions. Hydroencephaly usually becomes evident before 15 weeks of age and affected animals die within several days after notice.

 

References

(Earliest) J:93608 Kuwamura M, et al., Hemorrhagic hydrocephalus (hhy): a novel mutation on mouse chromosome 12. Brain Res Dev Brain Res. 2004 Aug 18;152(1):69-72
(Latest) J:180189 Mori N, et al., Ccdc85c encoding a protein at apical junctions of radial glia is disrupted in hemorrhagic hydrocephalus (hhy) mice. Am J Pathol. 2012 Jan;180(1):314-27
All references(2)