About   Help   FAQ
hhy Gene Detail
Summary
  • Symbol
    hhy
  • Name
    hemorrhagic hydrocephalus
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3505572
Location & Maps
more
  • Genetic Map
    Chromosome 12, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    1
  • Spontaneous
    1
Homozygous mutant mice display hydrocephalus, intracranial hemorrhage due to ventricular dilatation, and heterotopia in the subcortical regions. Hydroencephaly usually becomes evident before 15 weeks of age and affected animals die within several days after notice.
References
more
  • Summaries
    All 2
    Phenotypes 2
  • Earliest
    J:93608 Kuwamura M, et al., Hemorrhagic hydrocephalus (hhy): a novel mutation on mouse chromosome 12. Brain Res Dev Brain Res. 2004 Aug 18;152(1):69-72
  • Latest
    J:180189 Mori N, et al., Ccdc85c encoding a protein at apical junctions of radial glia is disrupted in hemorrhagic hydrocephalus (hhy) mice. Am J Pathol. 2012 Jan;180(1):314-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/22/2016
MGI 6.04
The Jackson Laboratory