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Zmiz1
Gene Detail
Symbol

Name
ID
Zmiz1
zinc finger, MIZ-type containing 1
MGI:3040693
Synonyms
Rai17, Zimp10
Feature Type
protein coding gene
Genetic Map
Chromosome 14
15.03 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:25459185-25666743 bp, + strand
From VEGA annotation of GRCm38

  207559 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10667  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zmiz1

Human
homologs
Human Homolog ZMIZ1, zinc finger, MIZ-type containing 1
NCBI Gene ID 57178
neXtProt AC  NX_Q9ULJ6
Human Synonyms  hZIMP10, MIZ, RAI17, TRAFIP10, ZIMP10
Human Chr (Location)  10q22.3; chr10:79068994-79316528 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(100) : Gene trapped(97) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display embryonic lethality during organogenesis with failure of yolk sac vascular remodeling and abnormal embryonic vascular development.
 
Interactions
Zmiz1 interacts with 419 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process artery morphogenesis, cell aging, ...
Component cytoplasm, intracellular membrane-bounded organelle, ...
Function metal ion binding, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (126)    Tissues (73)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 84
RT-PCR 42
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(15) Primer pair(2)
Microarray probesets(9)
Other database
links
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034637 VEGA Gene Model | MGI Sequence Detail 207559 C57BL/6J ±  kb
transcript OTTMUST00000087913 VEGA | MGI Sequence Detail 7482 Not Applicable 
polypeptide OTTMUSP00000047882 VEGA | MGI Sequence Detail 1072 Not Applicable 

For the selected sequences
All sequences(78) RefSeq(9) UniProt(7)
Polymorphisms
SNPs within 2kb(1283 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1285)
Protein-related
information
ResourceIDDescription
InterPro IPR004181 Zinc finger, MIZ-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000017683 zinc finger MIZ domain-containing protein 1
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory