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Zmiz1
Gene Detail
 Symbol
Name
ID
Zmiz1
zinc finger, MIZ-type containing 1
MGI:3040693
Synonyms Rai17, Zimp10
Feature Type protein coding gene
Genetic Map
Chromosome 14
15.03 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:25459185-25666743 bp, + strand
From VEGA annotation of GRCm38

  207559 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10667  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Zmiz1

Human
homologs
Human Homolog ZMIZ1, zinc finger, MIZ-type containing 1
NCBI Gene ID 57178
neXtProt AC  NX_Q9ULJ6
Human Synonyms  hZIMP10, MIZ, RAI17, TRAFIP10, ZIMP10
Human Chr (Location)  10q22.3; chr10:79068994-79316528 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(100) : Gene trapped(97) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display embryonic lethality during organogenesis with failure of yolk sac vascular remodeling and abnormal embryonic vascular development.
 
Interactions
Zmiz1 interacts with 419 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process artery morphogenesis, cell aging, ...
Component cytoplasm, nucleus
Function metal ion binding, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (126)    Tissues (73)    Images (26)
Theiler Stages: 2, 3, 11, 13, 15, 16, 17, 19, 20, 21, 22, 23, 24, 28
Assay TypeResults
RNA in situ 84
RT-PCR 42
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(15) Primer pair(2)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000034637 (Evidence)
Ensembl Gene ModelENSMUSG00000007817 (Evidence)
Entrez Gene328365 (Evidence)
DFCITC1576465, TC1589728, TC1590844, TC1591448, TC1606497, TC1614166, TC1638770, TC1659672, TC1668219
DoTSDT.101136732, DT.103583933, DT.40141602, DT.40149419, DT.533591, DT.91325520, DT.91336922, DT.94170325, DT.94266226, DT.97412783
Consensus CDS ProjectCCDS26873.1
International Mouse Knockout Project StatusZmiz1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034637 VEGA Gene Model | MGI Sequence Detail 207559 C57BL/6J ±  kb
transcript OTTMUST00000087913 VEGA | MGI Sequence Detail 7482 Not Applicable 
polypeptide OTTMUSP00000047882 VEGA | MGI Sequence Detail 1072 Not Applicable 

For the selected sequences
All sequences(75) RefSeq(9) UniProt(4)
Polymorphisms SNPs within 2kb(1283 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1285)
Protein-related
information
ResourceIDDescription
InterPro IPR004181 Zinc finger, MIZ-type
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000017683 zinc finger MIZ domain-containing protein 1
References (Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory