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Slc13a5
Gene Detail
Symbol

Name
ID
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
MGI:3037150
Synonyms
Indy, mINDY, NaC2/NaCT, Nact
Feature Type
protein coding gene
Genetic Map
Chromosome 11
43.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:72241994-72267222 bp, - strand
From VEGA annotation of GRCm38

  25229 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21941  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Slc13a5

Human
homologs
Human Homolog SLC13A5, solute carrier family 13 (sodium-dependent citrate transporter), member 5
NCBI Gene ID 284111
neXtProt AC  NX_Q86YT5
Human Synonyms  EIEE25, mIndy, NACT
Human Chr (Location)  17p13.1; chr17:6684713-6713421 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SLC13A5
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele display resistance to diet and age induced obesity, increased energy expenditure, improved glucose tolerance, and increased hepatic lipid oxidation.
 
Interactions
Slc13a5 interacts with 171 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 2
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(16) cDNA(13) Primer pair(3)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000006104 (Evidence)
Ensembl Gene ModelENSMUSG00000020805 (Evidence)
Entrez Gene237831 (Evidence)
UniGene340778
DFCITC1625782
DoTSDT.101167435
NIA Mouse Gene IndexU033024
Consensus CDS ProjectCCDS24983.1
International Mouse Knockout Project StatusSlc13a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006104 VEGA Gene Model | MGI Sequence Detail 25229 C57BL/6J ±  kb
transcript OTTMUST00000013794 VEGA | MGI Sequence Detail 3267 Not Applicable 
polypeptide OTTMUSP00000006394 VEGA | MGI Sequence Detail 572 Not Applicable 

For the selected sequences
All sequences(44) RefSeq(12) UniProt(4)
Polymorphisms
SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001898 Sodium/sulphate symporter
Protein Ontology PR:000014937 solute carrier family 13 member 5
References
(Earliest) J:88503 Inoue K, et al., Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates. Biochem J. 2004 Mar 15;378(Pt 3):949-57
(Latest) J:176732 Birkenfeld AL, et al., Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. Cell Metab. 2011 Aug 3;14(2):184-95
All references(29)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory