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Slc13a5
Gene Detail
Symbol

Name
ID
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
MGI:3037150
Synonyms
Indy, mINDY, NaC2/NaCT, Nact
Feature Type
protein coding gene
Genetic Map
Chromosome 11
43.95 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:72241994-72267222 bp, - strand
From VEGA annotation of GRCm38

  25229 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21941  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SLC13A5
Gene Tree: Slc13a5

Human
homologs
SLC13A5, solute carrier family 13 (sodium-dependent citrate transporter), member 5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 284111
neXtProt AC: NX_Q86YT5

Human Synonyms: EIEE25, mIndy, NACT

Human Chr (Location): 17p13.1; chr17:6684713-6713421 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SLC13A5

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Genomic Mutations involving Slc13a5 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null allele display resistance to diet and age induced obesity, increased energy expenditure, improved glucose tolerance, and increased hepatic lipid oxidation.
 
Interactions
Slc13a5 interacts with 170 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (3)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 2
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase slc13a5    NEW 
Molecular
reagents
All nucleic(16) cDNA(13) Primer pair(3)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000006104 (Evidence)
Ensembl Gene Model ENSMUSG00000020805 (Evidence)
Entrez Gene 237831 (Evidence)
UniGene 340778
DFCI TC1625782
DoTS DT.101167435
NIA Mouse Gene Index U033024
Consensus CDS Project CCDS24983.1
International Mouse Phenotyping Consortium Status Slc13a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006104 VEGA Gene Model | MGI Sequence Detail 25229 C57BL/6J ±  kb
transcript OTTMUST00000013794 VEGA | MGI Sequence Detail 3267 Not Applicable 
polypeptide OTTMUSP00000006394 VEGA | MGI Sequence Detail 572 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(10) UniProt(4)
Polymorphisms
SNPs within 2kb(103 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001898 Sodium/sulphate symporter
Protein Ontology PR:000014937 solute carrier family 13 member 5
References
(Earliest) J:88503 Inoue K, et al., Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates. Biochem J. 2004 Mar 15;378(Pt 3):949-57
(Latest) J:176732 Birkenfeld AL, et al., Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice. Cell Metab. 2011 Aug 3;14(2):184-95
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory