Slc13a5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
MGI:3037150

30 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc13a5^M1Btlr/Slc13a5⁺ C57BL/6J-Slc13a5^M1Btlr	decreased body weight	J:255297
Slc13a5^M1Btlr/Slc13a5^M1Btlr C57BL/6J-Slc13a5^M1Btlr	decreased body weight	J:255297
Slc13a5^m2Btlr/Slc13a5^m2Btlr C57BL/6J-Slc13a5^m2Btlr	decreased body weight	J:265142
Slc13a5^tm1.2Helf/Slc13a5⁺ B6.Cg-Slc13a5^tm1.2Helf	abnormal liver physiology	J:176732
	decreased body length	J:176732
	decreased body weight	J:176732
Slc13a5^tm1.2Helf/Slc13a5^tm1.2Helf B6.Cg-Slc13a5^tm1.2Helf	abnormal glucose homeostasis	J:176732
	abnormal glycerol level	J:176732
	abnormal hepatocyte mitochondrial morphology	J:176732
	abnormal hepatocyte physiology	J:176732
	abnormal liver morphology	J:176732
	abnormal liver physiology	J:176732
	abnormal metabolism	J:176732
	abnormal muscle physiology	J:176732
	abnormal susceptibility to weight gain	J:176732
	decreased body length	J:176732
	decreased body weight	J:176732
	decreased circulating glucose level	J:176732
	decreased circulating insulin level	J:176732
	decreased circulating lactate level	J:176732
	decreased liver triglyceride level	J:176732
	decreased susceptibility to age related obesity	J:176732
	decreased susceptibility to diet-induced obesity	J:176732
	decreased total body fat amount	J:176732
	improved glucose tolerance	J:176732
	increased carbon dioxide production	J:176732
	increased energy expenditure	J:176732
	increased insulin sensitivity	J:176732
	increased lean body mass	J:176732
	increased locomotor activity	J:176732
	increased muscle cell glucose uptake	J:176732
	increased oxygen consumption	J:176732
Slc13a5^{tm1b(EUCOMM)Hmgu}/Slc13a5^{tm1b(EUCOMM)Hmgu} C57BL/6N-Slc13a5^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal QT variability	J:211773
	increased grip strength	J:211773
	increased leukocyte cell number	J:211773
	short tibia	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23