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Foxi2 Gene Detail
Summary
  • Symbol
    Foxi2
  • Name
    forkhead box I2
  • Synonyms
    B130055A05Rik
Location &
Maps
more
  • Sequence Map
    Chr7:135012096-135015351 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 81.27 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3028075
 protein coding gene Chr7:135012037-135015351 (+)
129S1/SvImJ ENSMUSG00200025359
 protein coding gene Chr7:121564799-121568113 (+)
A/J ENSMUSG00195033024
 protein coding gene Chr7:126035448-126038762 (+)
AKR/J ENSMUSG00220016004
 protein coding gene Chr7:119503724-119507038 (+)
BALB/cJ ENSMUSG00180029014
 protein coding gene Chr7:122741607-122744921 (+)
C3H/HeJ ENSMUSG00175036081
 protein coding gene Chr7:123467774-123471088 (+)
C57BL/6NJ ENSMUSG00215043561
 protein coding gene Chr7:122730296-122733610 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030600
 protein coding gene Chr7:137581833-137585131 (+)
CAST/EiJ ENSTCUG00005045390
 protein coding gene Chr7:126051662-126054976 (+)
CBA/J ENSMUSG00210026156
 protein coding gene Chr7:123239147-123242461 (+)
DBA/2J ENSMUSG00185023492
 protein coding gene Chr7:127532209-127535523 (+)
FVB/NJ ENSMUSG00205038392
 protein coding gene Chr7:123200682-123203996 (+)
JF1/MsJ ENSUMUG00000026828
 protein coding gene Chr7:132593198-132596523 (+)
LP/J ENSMUSG00230037243
 protein coding gene Chr7:133668442-133671756 (+)
NOD/ShiLtJ ENSMUSG00190023035
 protein coding gene Chr7:123344217-123347531 (+)
NZO/HlLtJ ENSMUSG00225051645
 protein coding gene Chr7:131908017-131911331 (+)
PWK/PhJ ENSLUMG00010029435
 protein coding gene Chr7:121745783-121749097 (+)
SPRET/EiJ ENSMSPG00010030967
 protein coding gene Chr7:123069813-123073155 (+)
WSB/EiJ ENSIUOG00005034204
 protein coding gene Chr7:124034543-124037859 (+)



Homology
more
  • Human Ortholog
    FOXI2, forkhead box I2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FOXI2, forkhead box I2
  • Links
    NCBI Gene ID: 399823
    UniProt: Q6ZQN5

  • Chr Location
    10q26.2; chr10:127737185-127741183 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele are viable and fertile with no gross abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    95
  • cDNA Data
    14
  • Literature Summary
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 270004 NCBI Gene Model | MGI Sequence Detail 3256 C57BL/6J ±  kb
    transcript NM_183193 RefSeq | MGI Sequence Detail 2598 C57BL/6  
    polypeptide Q3I5G5 UniProt | EBI | MGI Sequence Detail 311 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      Genomic 1
      cDNA 14
      Primer pair 3
      Other 2

      Microarray probesets 1
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 13
      Gene Ontology 5
      Phenotypes 8
    • Earliest
      J:91257 Gray PA, et al., Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory