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Zfhx2 Gene Detail
Summary
  • Symbol
    Zfhx2
  • Name
    zinc finger homeobox 2
  • Synonyms
    zfh-5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2686934
    NCBI Gene: 239102
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55060262-55092324 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 28.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2686934
protein coding gene Chr14:55060262-55092432 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021339
protein coding gene Chr14:49061170-49093251 (-)
A/J MGP_AJ_G0021298
protein coding gene Chr14:48080722-48112751 (-)
AKR/J MGP_AKRJ_G0021274
protein coding gene Chr14:49830331-49862336 (-)
BALB/cJ MGP_BALBcJ_G0021302
protein coding gene Chr14:48058339-48090371 (-)
C3H/HeJ MGP_C3HHeJ_G0021082
protein coding gene Chr14:49518877-49552451 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021740
protein coding gene Chr14:51549313-51581885 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019287
protein coding gene Chr14:46485820-46518025 (-)
CAST/EiJ MGP_CASTEiJ_G0020601
protein coding gene Chr14:45766197-45801536 (-)
CBA/J MGP_CBAJ_G0021049
protein coding gene Chr14:53104780-53136838 (-)
DBA/2J MGP_DBA2J_G0021170
protein coding gene Chr14:47820705-47852748 (-)
FVB/NJ MGP_FVBNJ_G0021152
protein coding gene Chr14:47287468-47319449 (-)
LP/J MGP_LPJ_G0021244
protein coding gene Chr14:50110966-50143781 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021176
protein coding gene Chr14:52470119-52502158 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021767
protein coding gene Chr14:49014996-49046988 (-)
PWK/PhJ MGP_PWKPhJ_G0020348
protein coding gene Chr14:44360542-44392782 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020176
protein coding gene Chr14:44997567-45038650 (-)
WSB/EiJ MGP_WSBEiJ_G0020654
protein coding gene Chr14:49310050-49343545 (-)



Homology
more
  • Human Ortholog
    ZFHX2, zinc finger homeobox 2
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZFHX2, zinc finger homeobox 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MARSIS, ZFH5, ZFH-5, ZNF409
  • Links
    NCBI Gene ID: 85446
    neXtProt AC: NX_Q9C0A1
    UniProt: Q9C0A1

  • Chr Location
    14q11.2; chr14:23520855-23555949 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040721 Ensembl Gene Model | MGI Sequence Detail 32063 C57BL/6J ±  kb
transcript ENSMUST00000036328 Ensembl | MGI Sequence Detail 10397 Not Applicable  
polypeptide ENSMUSP00000045156 Ensembl | MGI Sequence Detail 2562 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 11
    Primer pair 8
    Other 1

    Microarray probesets 1
References
more
  • Summaries
    All 31
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:257654 Memic F, et al., Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory