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Slc9a5
Gene Detail
 Symbol
Name
ID
Slc9a5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
MGI:2685542
Synonyms LOC277973
Feature Type protein coding gene
Genetic Map
Chromosome 8
53.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr8:105348258-105369881 bp, + strand
From NCBI annotation of GRCm38

  21624 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:31247  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Slc9a5

Human
homologs
Human Homolog SLC9A5, solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
NCBI Gene ID 6553
neXtProt AC  NX_Q14940
Human Synonyms  NHE5
Human Chr (Location)  16q22.1; chr16:67248952-67272191 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Slc9a5 interacts with 166 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process hydrogen ion transmembrane transport, ion transport, ...
Component integral component of membrane, membrane
Function antiporter activity, sodium:proton antiporter activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (9)    Tissues (9)   
Theiler Stages: 1, 2, 3, 5, 28
Assay TypeResults
RT-PCR 9
cDNA source data(31)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) cDNA(31) Primer pair(2)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000014786 (Evidence)
Entrez Gene277973 (Evidence)
UniGene334766
DFCITC1601317
DoTSDT.480746
NIA Mouse Gene IndexU097446
Consensus CDS ProjectCCDS40457.1
International Mouse Knockout Project StatusSlc9a5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 277973 NCBI Gene Model | MGI Sequence Detail 21624 C57BL/6J ±  kb
transcript NM_001081332 RefSeq | MGI Sequence Detail 5222 Not Specified 
polypeptide NP_001074801 RefSeq | MGI Sequence Detail 898 Not Specified 

For the selected sequences
All sequences(30) RefSeq(17) UniProt(1)
Polymorphisms SNPs within 2kb(26 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006153 Cation/H+ exchanger
InterPro IPR018422 Cation/H+ exchanger, CPA1 family
InterPro IPR004709 Na+/H+ exchanger
InterPro IPR018410 Na+/H+ exchanger, isoforms 3/5
Protein Ontology PR:000015217 sodium/hydrogen exchanger 5
References (Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:202055 Siyanov V, et al., NHE1 is the sodium-hydrogen exchanger active in acute intracellular pH regulation in preimplantation mouse embryos. Biol Reprod. 2013 Jun;88(6):157
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory