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Pcdha8 Gene Detail
Summary
  • Symbol
    Pcdha8
  • Name
    protocadherin alpha 8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681879
    NCBI Gene: 353235
  • Member of
    Pcdha cluster
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr18:37125520-37320710 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1355 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2681879
protein coding gene Chr18:37125424-37320710 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0024270
protein coding gene Chr18:34167449-34357515 (+)
AKR/J MGP_AKRJ_G0024238
protein coding gene Chr18:35131263-35313391 (+)
BALB/cJ MGP_BALBcJ_G0024269
protein coding gene Chr18:34217499-34406362 (+)
C3H/HeJ MGP_C3HHeJ_G0024036
protein coding gene Chr18:35182439-35358175 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024711
protein coding gene Chr18:36663455-36867648 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022150
protein coding gene Chr18:34256190-34436126 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0024005
protein coding gene Chr18:37734865-37945878 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0024218
protein coding gene Chr18:35432977-35676922 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024138
protein coding gene Chr18:39175017-39218915 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024760
protein coding gene Chr18:34996711-35180644 (+)
PWK/PhJ MGP_PWKPhJ_G0023256
protein coding gene Chr18:34029432-34203479 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023060
protein coding gene Chr18:35248186-35441752 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PCDHA7, protocadherin alpha 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHA7, protocadherin alpha 7
  • Synonyms
    CNR4, CNRN4, CNRS4, CRNR4, PCDH-ALPHA7
  • Links
    NCBI Gene ID: 56141
    neXtProt AC: NX_Q9UN72
    UniProt: Q9UN72

  • Chr Location
    5q31.3; chr5:140834384-141012344 (+)  GRCh38.p7

  • Human Ortholog
    PCDHA9, protocadherin alpha 9
  • Synonyms
    PCDH-ALPHA9
  • Links
    NCBI Gene ID: 9752
    neXtProt AC: NX_Q9Y5H5
    UniProt: Q9Y5H5

  • Chr Location
    5q31.3; chr5:140847772-141012344 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 353235 NCBI Gene Model | MGI Sequence Detail 195191 C57BL/6J ±  kb
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4
References
more
  • Summaries
    All 22
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:67989 Wu Q, et al., Comparative dna sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 2001 Mar;11(3):389-404
  • Latest
    J:302805 Asai H, et al., Pcdhbeta deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination. Mol Brain. 2020 Jan 20;13(1):7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory