About   Help   FAQ
Polr3a
Gene Detail
 Symbol
Name
ID
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
MGI:2681836
Synonyms 9330175N20Rik, MGC:62420, RPC1, RPC155
Feature Type protein coding gene
Genetic Map
Chromosome 14
14.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:24448694-24487046 bp, - strand
From NCBI annotation of GRCm38

  38353 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5124  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Polr3a

Human
homologs
Human Homolog POLR3A, polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
NCBI Gene ID 11128
neXtProt AC  NX_O14802
Human Synonyms  ADDH, HLD7, hRPC155, RPC1, RPC155
Human Chr (Location)  10q22-q23; chr10:77975149-78029540 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human POLR3A
Alleles
and
phenotypes
All alleles(12) : Gene trapped(11) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process innate immune response, positive regulation of interferon-beta production, ...
Component DNA-directed RNA polymerase III complex, membrane
Function chromatin binding, DNA-directed RNA polymerase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22
Assay TypeResults
RNA in situ 94
cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000025280 (Evidence)
Entrez Gene218832 (Evidence)
DFCITC1600943, TC1609682, TC1610622, TC1623674, TC1658945
DoTSDT.101385307, DT.40140111, DT.40151097, DT.94188462
NIA Mouse Gene IndexU035313, U188663, U219496
EC2.7.7.6
Consensus CDS ProjectCCDS36828.1
International Mouse Knockout Project StatusPolr3a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 218832 NCBI Gene Model | MGI Sequence Detail 38353 C57BL/6J ±  kb
transcript NM_001081247 RefSeq | MGI Sequence Detail 4683 Not Specified 
polypeptide NP_001074716 RefSeq | MGI Sequence Detail 1390 Not Specified 

For the selected sequences
All sequences(35) RefSeq(5) UniProt(2)
Polymorphisms SNPs within 2kb(224 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015700 DNA-directed RNA polymerase III largest subunit
InterPro IPR000722 RNA polymerase, alpha subunit
InterPro IPR006592 RNA polymerase, N-terminal
InterPro IPR007080 RNA polymerase Rpb1, domain 1
InterPro IPR007066 RNA polymerase Rpb1, domain 3
InterPro IPR007083 RNA polymerase Rpb1, domain 4
InterPro IPR007081 RNA polymerase Rpb1, domain 5
Protein Ontology PR:000013000 DNA-directed RNA polymerase III subunit RPC1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:183694 Canella D, et al., A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver. Genome Res. 2012 Apr;22(4):666-80
All references(35)
Other
accession IDs
MGI:1924764

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory