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Polr3a Gene Detail
Summary
  • Symbol
    Polr3a
  • Name
    polymerase (RNA) III (DNA directed) polypeptide A
  • Synonyms
    9330175N20Rik, MGC:62420, RPC1, RPC155
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681836
    NCBI Gene: 218832
Location & Maps
more
  • Sequence Map
    Chr14:24448694-24487046 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      38353 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 14.40 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    POLR3A, polymerase (RNA) III subunit A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    POLR3A, polymerase (RNA) III subunit A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ADDH, HLD7, hRPC155, RPC1, RPC155
  • Links
    NCBI Gene ID: 11128
    neXtProt AC: NX_O14802

  • Chr Location
    10q22.3; chr10:77975149-78029540 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5124
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: POLR3A
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human POLR3A associations

Human Disease Mouse Models
       Leukodystrophy, Hypomyelinating, 7, with or without Oligodontia and/or Hypogonadotropic Hypogonadism; HLD7   OMIM: 607694
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025280 Ensembl Gene Model | MGI Sequence Detail 38353 C57BL/6J ±  kb
transcript ENSMUST00000026322 Ensembl | MGI Sequence Detail 4683 Not Applicable  
polypeptide ENSMUSP00000026322 Ensembl | MGI Sequence Detail 1390 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    225 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
Other
Accession IDs
less
MGI:1924764
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:183694 Canella D, et al., A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver. Genome Res. 2012 Apr;22(4):666-80

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory