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Polr3a
Gene Detail
Symbol

Name
ID
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
MGI:2681836
Synonyms
9330175N20Rik, MGC:62420, RPC1, RPC155
Feature Type
protein coding gene
Genetic Map
Chromosome 14
14.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr14:24448694-24487046 bp, - strand
From Ensembl annotation of GRCm38

  38353 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5124  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: POLR3A
Gene Tree: Polr3a

Human
homologs
POLR3A, polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 11128
neXtProt AC: NX_O14802

Human Synonyms: ADDH, HLD7, hRPC155, RPC1, RPC155

Human Chr (Location): 10q22.3; chr10:77975149-78029540 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human POLR3A

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Gene trapped(11) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Polr3a interacts with 109 markers (Mir7-1, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 94
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase polr3a ; ZFIN polr3a    NEW 
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000025280 (Evidence)
Entrez Gene 218832 (Evidence)
DFCI TC1658945, TC1623674, TC1610622, TC1609682, TC1600943
DoTS DT.101385307, DT.94188462, DT.40140111, DT.40151097
NIA Mouse Gene Index U035313, U219496, U188663
EC 2.7.7.6
Consensus CDS Project CCDS36828.1
International Mouse Phenotyping Consortium Status Polr3a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025280 Ensembl Gene Model | MGI Sequence Detail 38353 C57BL/6J ±  kb
transcript ENSMUST00000026322 Ensembl | MGI Sequence Detail 4683 Not Applicable 
polypeptide ENSMUSP00000026322 Ensembl | MGI Sequence Detail 1390 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(5) UniProt(2)
Polymorphisms
SNPs within 2kb(224 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR015700 DNA-directed RNA polymerase III largest subunit
InterPro IPR000722 RNA polymerase, alpha subunit
InterPro IPR006592 RNA polymerase, N-terminal
InterPro IPR007080 RNA polymerase Rpb1, domain 1
InterPro IPR007066 RNA polymerase Rpb1, domain 3
InterPro IPR007083 RNA polymerase Rpb1, domain 4
InterPro IPR007081 RNA polymerase Rpb1, domain 5
Protein Ontology PR:000013000 DNA-directed RNA polymerase III subunit RPC1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:183694 Canella D, et al., A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver. Genome Res. 2012 Apr;22(4):666-80
All references(32)
Other
accession IDs
MGI:1924764

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory