Polr3a
Gene Detail

Symbol Name ID

Polr3a polymerase (RNA) III (DNA directed) polypeptide A MGI:2681836

Synonyms

9330175N20Rik, MGC:62420, RPC1, RPC155

Feature Type

protein coding gene

Genetic Map

Chromosome 14

14.40 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr14:24448694-24487046 bp, - strand From NCBI annotation of GRCm38   38353 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:5124  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Polr3a

Human homologs

Human Homolog		POLR3A, polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
NCBI Gene ID		11128
neXtProt AC		NX_O14802
Human Synonyms		ADDH, HLD7, hRPC155, RPC1, RPC155
Human Chr (Location)		10q22-q23; chr10:79734907-79789298 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human POLR3A

Alleles and phenotypes

All alleles(12) : Targeted(1) Gene trapped(11)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	innate immune response, positive regulation of interferon-beta production, ...
Component	nucleus
Function	chromatin binding, DNA-directed RNA polymerase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (94)    Tissues (94)   
Theiler Stages: 22

Assay Type	Results
RNA in situ	94

cDNA source data(8)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(9) cDNA(9)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000025280 (Evidence)
Entrez Gene	218832 (Evidence)
DFCI	TC1600943, TC1609682, TC1610622, TC1623674, TC1658945
DoTS	DT.101385307, DT.40140111, DT.40151097, DT.94188462
NIA Mouse Gene Index	U035313, U188663, U219496
EC	2.7.7.6
Consensus CDS Project	CCDS36828.1
International Mouse Knockout Project Status	Polr3a

Sequences

Length	Strain/Species
genomic	218832	NCBI Gene Model | MGI Sequence Detail	38353	C57BL/6J
transcript	NM_001081247	RefSeq | MGI Sequence Detail	4683	Not Specified
polypeptide	NP_001074716	RefSeq | MGI Sequence Detail	1390	Not Specified

All sequences(33) RefSeq(3) UniProt(2)

Polymorphisms

SNPs(224 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR015700	DNA-directed RNA polymerase III largest subunit
InterPro	IPR000722	RNA polymerase, alpha subunit
InterPro	IPR006592	RNA polymerase, N-terminal
InterPro	IPR007080	RNA polymerase Rpb1, domain 1
InterPro	IPR007066	RNA polymerase Rpb1, domain 3
InterPro	IPR007083	RNA polymerase Rpb1, domain 4
InterPro	IPR007081	RNA polymerase Rpb1, domain 5
Protein Ontology	PR:000013000	DNA-directed RNA polymerase III subunit RPC1

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:183694 Canella D, et al., A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver. Genome Res. 2012 Apr;22(4):666-80
All references(33)

Other accession IDs

MGI:1924764