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Slitrk1
Gene Detail
 Symbol
Name
ID
Slitrk1
SLIT and NTRK-like family, member 1
MGI:2679446
Synonyms 3200001I04Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
56.78 cM, cytoband E3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:108909991-108914239 bp, - strand
From Ensembl annotation of GRCm38

  4249 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:14174  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Slitrk1

Human
homologs
Human Homolog SLITRK1, SLIT and NTRK-like family, member 1
NCBI Gene ID 114798
neXtProt AC  NX_Q96PX8
Human Synonyms  LRRC12, TTM
Human Chr (Location)  13q31.1; chr13:83877205-83882393 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human SLITRK1
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele display hypoactivity, reduced male body weight, elevated anxiety- and depression-like behavior, increased norepinephrine content in brain, and partial postnatal lethality.
 
Human Diseases Modeled Using Mouse Slitrk1 (1)    Alleles Annotated to Human Diseases(1)   
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process adult behavior, axonogenesis, ...
Component integral component of membrane, membrane
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (7 records)
Data Summary: Results (273)    Tissues (82)    Images (23)
Theiler Stages: 6, 7, 9, 11, 13, 15, 17, 19, 20, 21, 22, 23, 24, 25, 26, 28
Assay TypeResults
RNA in situ 220
Northern blot 35
Western blot 18
cDNA source data(32)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(34) cDNA(32) Other(2)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000075478 (Evidence)
Entrez Gene76965 (Evidence)
UniGene257268
DFCITC1701034
DoTSDT.101139273
NIA Mouse Gene IndexU135089
Consensus CDS ProjectCCDS27325.1
International Mouse Knockout Project StatusSlitrk1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075478 Ensembl Gene Model | MGI Sequence Detail 4249 C57BL/6J ±  kb
transcript ENSMUST00000100322 Ensembl | MGI Sequence Detail 4249 Not Applicable 
polypeptide ENSMUSP00000097897 Ensembl | MGI Sequence Detail 696 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(4)
Polymorphisms SNPs within 2kb(37 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
InterPro IPR001611 Leucine-rich repeat
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
InterPro IPR003591 Leucine-rich repeat, typical subtype
Protein Ontology PR:000015237 SLIT and NTRK-like protein 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199865 Kabayama M, et al., Rines E3 Ubiquitin Ligase Regulates MAO-A Levels and Emotional Responses. J Neurosci. 2013 Aug 7;33(32):12940-53
All references(37)
Other
accession IDs
MGI:1924215

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory